Explorer les evidences

0,9 %The range of foetal haemoglobin (HbF) levels in sickle cell anaemia patients in Nigeria was 0.9% to 16.7%.

Nigeriadrépanocytosepublié 1990European journal of haematologyeurope_pmcdocument de 5 observations

60 %Among 3622 enrolled sickle cell disease patients in Nigeria, 60% had experienced bone pain crisis.

Nigeriabone pain crisis · drépanocytosepublié 2020Blood cells, molecules & diseaseseurope_pmcdocument de 16 observations

14,9 %Chronic hepatitis B infection was the most prevalent complication, seen in 14.9% of the children.

Nigeriadrépanocytose · hépatite Bpublié 2021West African journal of medicinePubMeddocument de 10 observations

57,6 %Among 85 children with mild sickle cell disease, 49 (57.6%) had ocular abnormalities.

Nigeriadrépanocytosepublié 2021European journal of ophthalmologyPubMeddocument de 3 observations

99 %For HbAC phenotype, isoelectric focusing showed a specificity of 99%.

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 23 observations

50,3 %In 50.3% of encounters, patients with sickle cell disease managed by short-term emergency department observation care were successfully managed without requiring further care.

Nigeriadrépanocytoseobservé July 2017 to June 2019publié 2020Transactions of the Royal Society of Tropical Medicine and HygienePubMeddocument de 6 observations

25,7 %Automated red cell exchange for sickle cell disease accounted for 25.7% of procedures at one center in Nigeria.

NigeriadrépanocytosePubMeddocument de 6 observations

18,7 %Overall prevalence of sickle cell trait (AS) was 18.7%.

Nigeriadrépanocytose · trait drépanocytairepublié 2021BMC pregnancy and childbirtheurope_pmcdocument de 4 observationsDOI 10.1186/s12884-021-03974-4

77,7 %In a cohort of 193 children with sickle cell disease in Nigeria, peak systolic blood velocity (PSV) was normal in 150 (77.7%), high in 7 (3.6%), and conditional in 36 (18.7%).

Nigeriadrépanocytosepublié 2023Archives of disease in childhoodPubMeddocument de 5 observations

2,64 odds_ratioIn multivariate analysis, tingling was associated with painful crisis with an odds ratio of 2.64.

NigeriadrépanocytosePubMeddocument de 10 observations

20,8 %The prevalence of myocardial ischemia measuring electrocardiography alone in children with sickle cell anemia in steady state was 20.8%.

Nigeriadrépanocytose · myocardial ischemiaobservé 2019publié 2024Journal of tropical pediatricsPubMeddocument de 6 observations

2,4 %7 (2.4%) of the caregivers disagreed that Newborn Screening for Sickle Cell Disease helps in the early detection and management of Sickle Cell Disease.

Nigeriadrépanocytosepublié 2024Frontiers in public healtheurope_pmcdocument de 8 observations

4 foldPatients with the BEN/SEN haplotype showed a four-fold lower frequency of painful episodes compared to other haplotypes.

Nigeriadrépanocytosepublié 2021The Journal of international medical researchPubMeddocument de 5 observations

27,92 yearsThe mean age of the SCD participants was 27.92 years.

Nigeriadrépanocytosepublié 2021ImmunohematologyPubMeddocument de 7 observations

39,6 %Fifty-three (39.6%) of the children had hepatobiliary abnormalities.

Nigeriadrépanocytosepublié 2021West African journal of medicinePubMeddocument de 10 observations

34 %Among 108 children who completed the feasibility trial for managing severe acute malnutrition in older children with sickle cell anemia in Nigeria, 34% (n = 37) had very low food security.

Nigeriadrépanocytose · malnutritionpublié 2025Pediatric blood & cancerPubMeddocument de 4 observations

19,2 %Among 26 alloimmunized sickle cell disease participants, Kell alloantibodies were observed in 19.2%.

Nigeriadrépanocytosepublié 2025Transfusion and apheresis science : official journal of the World Apheresis Association : europe_pmcdocument de 9 observations

Higher malondialdehyde (MDA) level was associated with very severe vaso-occlusive crisis in sickle cell anaemia individuals.

Nigeriadrépanocytose · vaso-occlusive crisispublié 2021African health sciencesPubMeddocument de 7 observations

-0,06 kappaMeasures of agreement between ECG and cTnT in detecting myocardial injury were poor during the follow-up steady state (κ -0.06, p = 0.63).

Nigeriadrépanocytosepublié 2020Paediatrics and international child healtheurope_pmcdocument de 8 observations

4,15 cmLeft kidney breadth was significantly greater in sickle cell anemia patients (4.15 ± 0.92 cm vs. 3.79 ± 0.48 cm).

Nigeriadrépanocytosepublié 2023Nigerian journal of clinical practicePubMeddocument de 9 observations

68 patientsSixty-eight had leg ulcers.

Nigeriadrépanocytosepublié 2021Hematology (Amsterdam, Netherlands)PubMeddocument de 16 observations

7,5 %Socio-demographic factors explained 7.5% of the variance in utility score in people with sickle cell disease.

Nigeriadrépanocytosepublié 2019PloS onePubMeddocument de 5 observations

No severe adverse effects were observed with the simplified hydroxyurea dosing regimen in paediatric sickle cell anaemia patients in South East Nigeria.

Nigeriadrépanocytoseobservé 2022–2024publié 2025BMC pediatricsPubMeddocument de 3 observations

39 %Among 138 newly diagnosed sickle cell disease patients, 39% (0.63% SCD prevalence) were adults and 61% (1% SCD prevalence) were in the pediatric age-group.

Nigeriadrépanocytoseobservé 2013 to 2014publié 2022The Pan African medical journalPubMeddocument de 9 observations

Serum bilirubin levels differed significantly among young Nigerian SCA patients when differentiated by UGT1A1 (TA)n genotypes (p < 0.05).

Nigeriadrépanocytosepublié 2019BMC medical geneticsPubMeddocument de 6 observations