Explorer les evidences

53,1 %53.1% of senior secondary school students in Surulere Local Government Area, Lagos, Nigeria knew sickle cell disease was an inherited condition.

Nigeriadrépanocytosepublié 2022African journal of primary health care & family medicinePubMeddocument de 11 observations

373 mFunctional status assessed by six-minute walk test was 373.00 ± 60.40 m in sickle cell patients versus 403.83 ± 72.87 m in controls (p=0.021).

Nigeriadrépanocytosepublié 2022West African journal of medicinePubMeddocument de 8 observations

1,1 %Among 3622 enrolled sickle cell disease patients in Nigeria, 1.1% had pulmonary hypertension.

Nigeriadrépanocytose · pulmonary hypertensionpublié 2020Blood cells, molecules & diseaseseurope_pmcdocument de 16 observations

The copper-to-zinc ratio was higher in sickle cell anaemia patients than in controls, with a p-value less than 0.001.

Nigeriadrépanocytosepublié 2019African health sciencesPubMeddocument de 6 observations

68,4 %The risk of prolonged QTc interval was 68.4% during vaso-occlusive crisis in children with sickle cell anemia.

Nigeriadrépanocytosepublié 2021HemoglobinPubMeddocument de 5 observations

13 %Approximately 13% of Sickle Cell Disease patients in Nigeria benefit from Hydroxyurea therapy.

Nigeriadrépanocytosepublié 2025PloS oneeurope_pmcdocument de 2 observations

62 percentThe median ejection fraction of SCA patients was 62.00 (IQR = 55.0–67.0), significantly less than that of controls, which was 68.00 (IQR = 65.8–73.0).

Nigeriadrépanocytosepublié 2026BMC cardiovascular disordersPubMeddocument de 6 observations

2,4 %Sickle Cell Disease was the third leading indirect cause of maternal mortality, accounting for 2.4% of cases.

Nigeriadrépanocytoseobservé 2007-2019publié 2022BMC pregnancy and childbirthPubMeddocument de 10 observations

61 %At the 40% threshold, 61% of the poorest quartile of sickle cell disease patients experienced catastrophic expenditure.

Nigeriadrépanocytosepublié 2022PloS onePubMeddocument de 5 observations

44,9 %Ziziphus mauritiana at the high dose of 0.5 mg/ml caused a reduction in percentage of sickle red cells from 44.9% to 20.5% at 150 minutes.

Nigeriadrépanocytosepublié 2020West African journal of medicineeurope_pmcdocument de 3 observations

28,87 yearsThe mean age of the sickle cell patients was 28.87 ± 7.89 years.

Nigeriadrépanocytosepublié 2022West African journal of medicinePubMeddocument de 8 observations

71 %Chloroquine was found in the blood of 71% of homozygous alpha+-thalassaemic children.

Nigeriadrépanocytosepublié 2001Tropical medicine & international health : TM & IHeurope_pmcdocument de 8 observations

6,3 %Among 490 analysed alleles from 245 homozygous sickle cell disease patients in Nigeria, 31 (6.3%) had the Cameroon haplotype.

Nigeriadrépanocytosepublié 2021The Journal of international medical researchPubMeddocument de 5 observations

1 z_scoreNigerian SCA patients (n=154) had significant reductions in both FEV and FVC of ~1 z-score compared with local controls (n=364).

Nigeriadrépanocytosepublié 2019ThoraxPubMeddocument de 7 observations

7,6 %In a cross-sectional study of 405 Nigerian children, 7.6% were homozygous for alpha+-thalassaemia.

Nigeriadrépanocytosepublié 2001Tropical medicine & international health : TM & IHeurope_pmcdocument de 8 observations

69,1 %Hydroxyurea dose escalation beyond 20 mg/kg/day was required to attain significant reductions in the time-averaged mean of maximal velocities in 69.1% of the cases.

Nigeriadrépanocytosepublié 2021Pediatric blood & cancerPubMeddocument de 5 observations

150 000 infantsAn estimated 150,000 infants with sickle cell anemia are born annually in Nigeria.

Nigeriadrépanocytosepublié 2021Pediatric neurologyPubMeddocument de 4 observations

87,74 %In the study, 87.74% of children with sickle cell anaemia had mild disease severity.

Nigeriadrépanocytosepublié 2024West African journal of medicinePubMeddocument de 9 observations

5 patientsFive (8.6%) of the patients with acute leukaemia also had sickle cell disease.

Nigeriadrépanocytose · leukaemiapublié 2020African health sciencesPubMeddocument de 3 observations

40,1 %Pneumonia accounted for 40.1% of respiratory morbidities among sickle cell disease patients.

Nigeriadrépanocytose · pneumonieobservé 2012 to 2021publié 2024PloS onePubMeddocument de 12 observations

1,52 ng/mlWomen with HbSS had significantly lower median AMH of 1.52 ng/ml compared to the HbAA group with median AMH of 3.80 ng/ml.

Nigeriadrépanocytosepublié 2026Scientific reportsPubMeddocument de 7 observations

46,2 %The most used medical coping mechanism for priapism among male patients with sickle cell disease in Ibadan, Nigeria, was cold shower, used by 46.2%.

Nigeriadrépanocytosepublié 2020West African journal of medicinePubMeddocument de 9 observations

97 %97.0% of senior secondary school students in Surulere Local Government Area, Lagos, Nigeria had a positive attitude towards sickle cell disease.

Nigeriadrépanocytosepublié 2022African journal of primary health care & family medicinePubMeddocument de 11 observations

19 casesGroup 1 (SCD) comprised 19 (27.1%) Hb SS and 16 (22.9%) Hb SC.

Nigeriadrépanocytosepublié 2025The Nigerian postgraduate medical journalPubMeddocument de 6 observations

3,19 cmMean left ventricular internal diameter in systole was 3.19 ± 0.57 cm in sickle cell patients versus 2.81 ± 0.45 cm in controls (p=0.000).

Nigeriadrépanocytosepublié 2022West African journal of medicinePubMeddocument de 8 observations