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3 603 individualsA total of 3603 newborn babies and infants younger than 9 months were screened for sickle cell disease at five primary health-care centres between July 14, 2017, and September 3, 2019.

Nigeriadrépanocytoseobservé July 14, 2017 to September 3, 2019publié 2020The Lancet. Haematologyeurope_pmcdocument de 3 observations

82,4 %Twenty-eight (82.4%) SCA children had elevated serum cTnT during VOC.

Nigeriadrépanocytosepublié 2020Paediatrics and international child healtheurope_pmcdocument de 8 observations

99,2 %Among SCD patients, 130 (99.2%) were extensive metabolizers and 1 (0.8%) was a poor metabolizer of proguanil.

Nigeriadrépanocytosepublié 2016Pharmacology research & perspectiveseurope_pmcdocument de 5 observations

48,9 %ECG abnormalities were recorded in 22 out of 45 (48.9%) pediatric sickle cell anaemia patients in steady state.

Nigeriadrépanocytoseobservé 2023publié 2025BMC pediatricsPubMeddocument de 16 observations

2,3 %Among the 88 high-risk staff, 2.3% had sickle cell disease.

Nigeriadrépanocytosepublié 2020The Pan African medical journalPubMeddocument de 11 observations

148 patientsOf the 219 recorded, 148 of the patients had been transfused in the past.

Nigeriadrépanocytosepublié 2021Hematology (Amsterdam, Netherlands)PubMeddocument de 16 observations

0,7 %Liver cirrhosis was observed in 0.7% of the children.

Nigeriadrépanocytose · liver cirrhosispublié 2021West African journal of medicinePubMeddocument de 10 observations

31,7 %The overall return rate for acute care within 1 week for either persistence of symptoms or any other complaint among children with sickle cell disease managed by short-term emergency department observation care was 31.7%.

Nigeriadrépanocytoseobservé July 2017 to June 2019publié 2020Transactions of the Royal Society of Tropical Medicine and HygienePubMeddocument de 6 observations

6,8 %Stroke occurred in 6.8% of the 133 children with sickle cell disease.

NigeriaAVC · drépanocytoseobservé March 2022 and February 2025PubMeddocument de 8 observations

98,2 %The diagnostic specificity of SickleSCAN™ for sickle cell disease (Hb SS and Hb SC) was 98.2%.

Nigeriadrépanocytosepublié 2017Hemoglobineurope_pmcdocument de 5 observations

3,8 %Among 26 alloimmunized sickle cell disease participants, MNS alloantibodies were observed in 3.8%.

Nigeriadrépanocytose · MNS alloantibodiespublié 2025Transfusion and apheresis science : official journal of the World Apheresis Association : europe_pmcdocument de 9 observations

50 %The number of subjects who had more than two episodes of painful crises reduced from 27 (50%) to 2 (2.7%) after 12 months of hydroxyurea therapy.

Nigeriadrépanocytosepublié 2020Journal of tropical pediatricsPubMeddocument de 4 observations

7 x10⁹/LAbsolute neutrophil count in steady state subjects was 7.0 ± 2.1.

Nigeriadrépanocytosepublié 2022The Pan African medical journalPubMeddocument de 14 observations

17,6 %Serum cTnT was elevated in six (17.6%) SCA children during the steady state.

Nigeriadrépanocytosepublié 2020Paediatrics and international child healtheurope_pmcdocument de 8 observations

28,24 mmThe mean trans annular plane systolic excursion (TAPSE) in children with sickle cell anaemia was 28.24 ± 5.23 mm.

Nigeriadrépanocytosepublié 2020BMC pediatricsPubMeddocument de 8 observations

72,5 %The majority (72.5%) of the SCD participants had received at least 1 unit of red blood cell transfusion in their lifetime.

Nigeriadrépanocytosepublié 2021ImmunohematologyPubMeddocument de 7 observations

In a randomized controlled trial in southwest Nigeria, low-dose aspirin (100 mg daily) did not significantly reduce the composite primary outcome of intrauterine growth restriction, perinatal mortality, or miscarriage in pregnant women with haemoglobin SS or SC.

Nigeriadrépanocytosepublié 2026The Lancet. Global healthPubMeddocument de 13 observations

78 %A significantly higher proportion of children with sickle cell disease (78%) had high ferritin status compared with controls (48.3%).

Nigeriadrépanocytosepublié 2023West African journal of medicinePubMeddocument de 8 observations

73 %Seventy-three percent of the respondents noted that hydroxyurea reduced transfusion rates in patients with sickle cell disease.

Nigeriadrépanocytosepublié 2019HemoglobinPubMeddocument de 7 observations

29,2 %Among 209 parents of children with SCD in Ibadan, Nigeria, 29.2% discovered their sickle cell phenotype only after having a child with SCD or during a health crisis.

Nigeriadrépanocytosepublié 2025BMC public healthPubMeddocument de 5 observations

0,07 kappaMeasures of agreement between ECG and cTnT in detecting myocardial injury were poor during VOC (κ 0.07, p = 0.68).

Nigeriadrépanocytosepublié 2020Paediatrics and international child healtheurope_pmcdocument de 8 observations

6 %Among 3622 enrolled sickle cell disease patients in Nigeria, 6.0% had avascular necrosis of bone.

Nigeriaavascular necrosis of bone · drépanocytosepublié 2020Blood cells, molecules & diseaseseurope_pmcdocument de 16 observations

39 %At the end of the trial, 39% of participants improved their body mass index z score to ≥-3.0.

Nigeriadrépanocytosepublié 2023Blood advancesPubMeddocument de 6 observations

515 000 birthsGlobally, approximately 515000 babies are born with sickle cell disease annually.

Nigeriadrépanocytosepublié 2024BMJ openeurope_pmcdocument de 2 observations

5 295 patients5,295 people living with sickle cell disease had at least one follow-up visit with their clinical data updated.

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 8 observations