Explorer les evidences

Two National Institutes of Health-funded primary stroke prevention trials included initial hydroxyurea treatment for children with sickle cell anemia and abnormal transcranial Doppler velocities in Nigeria.

Nigeriadrépanocytosepublié 2021Pediatric neurologyPubMeddocument de 4 observations

4,2 %The overall prevalence of subclinical hypothyroidism among children with sickle cell anaemia in this study was 4.2%.

Nigeriadrépanocytose · subclinical hypothyroidismpublié 2023Ethiopian journal of health sciencesPubMeddocument de 7 observations

98,9 %After a health education session, 98.9% of pregnant women understood that both parents must have at least one gene for someone to have sickle cell disease, compared to 77.5% before the session.

Nigeriadrépanocytosepublié 2024BMC pregnancy and childbirthPubMeddocument de 6 observations

42 patientsAmong the 257 enrolled sickle cell anaemia patients, 42 had proteinuric chronic kidney disease.

Nigeriadrépanocytose · proteinuric chronic kidney diseaseobservé January 2013 to April 2018publié 2021Hematology/oncology and stem cell therapyPubMeddocument de 6 observations

33,3 %A third of the study participants (33.3%) expressed a contrary standpoint regarding prioritising sickle cell screening in their relationships.

Nigeriadrépanocytosepublié 2022Hematology (Amsterdam, Netherlands)PubMeddocument de 6 observations

65,5 %Among the 58 patients with sickle cell anemia, 65.5% were males.

Nigeriadrépanocytosepublié 2023Nigerian journal of clinical practicePubMeddocument de 9 observations

65 %The pediatric department (CHER+CHOP) recorded the highest proportion of sickle cell disease cases at 65%.

Nigeriadrépanocytoseobservé 2013 to 2014publié 2022The Pan African medical journalPubMeddocument de 9 observations

1,16 cmSickle cell anemia subjects had a smaller mean inferior vena cava diameter than non-SCA subjects (1.16 cm ± 0.29 vs. 1.25 cm ± 0.33).

Nigeriadrépanocytosepublié 2023Nigerian journal of clinical practicePubMeddocument de 9 observations

73,4 %Three-quarters of the participants (73.4%) supported the need for contextual legislation to prohibit marriage between two sickle cell carriers.

Nigeriadrépanocytosepublié 2022Hematology (Amsterdam, Netherlands)PubMeddocument de 6 observations

2,7 x10¹²/LRed blood cell count in steady state subjects was 2.7 ± 0.4.

Nigeriadrépanocytosepublié 2022The Pan African medical journalPubMeddocument de 14 observations

72,4 %Isoelectric focusing (IEF) tests identified 370 (72.4%) HbAA, 133 (26.0%) HbAS, 5 (1.0%) HbSS, and 3 (0.6%) HbAC phenotypes among 511 newborns.

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 23 observations

15,5 %Among 308 children with sickle cell disease in Nigeria, cerebral artery blood velocity was conditional in 48 (15.5%).

Nigeriadrépanocytosepublié 2023Archives of disease in childhoodPubMeddocument de 5 observations

The mean heart rate in crisis was higher than in steady state.

Nigeriadrépanocytosepublié 2020Cardiology in the youngPubMeddocument de 6 observations

52 %Abnormal LV geometry was detected in 52% of the SCA patients.

Nigeriadrépanocytosepublié 2026BMC cardiovascular disordersPubMeddocument de 6 observations

55,6 %Among 135 physicians caring for SCD patients in a southwestern state of Nigeria, 75 (55.6%) were willing to recommend the national government newborn screening program.

Nigeriadrépanocytosepublié 2020TheScientificWorldJournalPubMeddocument de 9 observations

73,6 %Among the healthcare workers, 39 (73.6%) were aware of Newborn Screening for Sickle Cell Disease.

Nigeriadrépanocytosepublié 2024Frontiers in public healtheurope_pmcdocument de 8 observations

No patients with chronic leg ulcer was diabetic.

Nigeriadiabète (non précisé) · drépanocytose · leg ulcersobservé 2015publié 2020African journal of laboratory medicineeurope_pmcdocument de 3 observations

34 000 patientsOver 34,000 patients with sickle cell disease are enrolled in the SickleInAfrica consortium registry.

Nigeriadrépanocytosepublié 2025BMJ global healtheurope_pmcdocument de 4 observations

-0,1 correlation_coefficientBMI correlated negatively with left ventricular mass index (LVMI) among the subjects (r = -0.1, P = 0.53).

Nigeriadrépanocytosepublié 2021Nigerian journal of clinical practicePubMeddocument de 3 observations

0,24 %The estimated average birth prevalence of HbSC in Nigeria was 0.24%.

Nigeriadrépanocytosepublié 2021The Lancet. Haematologyeurope_pmcdocument de 6 observations

Myocardial ischaemia scores were higher in patients with crisis than in those in steady state.

Nigeriadrépanocytosepublié 2020Cardiology in the youngPubMeddocument de 6 observations

60 %The prevalence of ocular abnormalities among 120 children aged 5 to 15 years with sickle cell disease in steady state was 60.0%.

Nigeriadrépanocytosepublié 2021European journal of ophthalmologyPubMeddocument de 3 observations

23,6 yearsThe mean age of male patients with sickle cell disease in Ibadan, Nigeria, was 23.6 years with a standard deviation of 8.8 years.

Nigeriadrépanocytosepublié 2020West African journal of medicinePubMeddocument de 9 observations

10,8 %The prevalence of HbSC was 10.8% among sickle cell disease patients.

Nigeriadrépanocytose · HbSCpublié 2022Mediterranean journal of hematology and infectious diseaseseurope_pmcdocument de 17 observationsDOI 10.4084/mjhid.2022.001

1 213 casesOf the 7,256 children and adolescents with sickle cell disease, 1,213 (16.7%) had respiratory morbidities.

Nigeriadrépanocytose · respiratory morbiditiesobservé 2012 to 2021publié 2024PloS onePubMeddocument de 12 observations