Explorer les evidences

84 %In a cohort of 115 children with sickle cell disease in Nigeria, time averaged mean of the maximum blood velocity (TAMMV) was normal in 96 (84%), high in 7 (6%), and conditional in 12 (10%).

Nigeriadrépanocytosepublié 2023Archives of disease in childhoodPubMeddocument de 5 observations

25 %About 25% of adults have the sickle cell gene.

Nigeriadrépanocytosepublié 2022The Pan African medical journalPubMeddocument de 7 observations

43,9 %Parahydroxybenzoic acid (PHBA) caused a reduction in percentage of sickle red cells from 43.9% to 14.6% at 150 minutes.

Nigeriadrépanocytosepublié 2020West African journal of medicineeurope_pmcdocument de 3 observations

23,1 %Among male patients with sickle cell disease in Ibadan, Nigeria, apathy for sexual intercourse was reported in 23.1% of respondents.

Nigeriadrépanocytosepublié 2020West African journal of medicinePubMeddocument de 9 observations

0,447 secondsThe median QTc interval was 0.447 seconds (interquartile range: 0.438–0.459 seconds) during vaso-occlusive crisis in children with sickle cell anemia.

Nigeriadrépanocytosepublié 2021HemoglobinPubMeddocument de 5 observations

25,1 yearsThe mean age of the 503 genotyped SCD patients was 25.1 years.

Nigeriadrépanocytosepublié 2025Gates open researchPubMeddocument de 5 observations

100 %CAE did not identify any of the 2 HbAC individuals that were correctly identified by PCR and both HemotypeSC and HPLC, representing 100% HbAC misdiagnosis.

Nigeriadrépanocytosepublié 2021Global pediatric healtheurope_pmcdocument de 5 observations

33,9 %In the study, 33.9% of children with sickle cell anaemia had known steady state PCV.

Nigeriadrépanocytosepublié 2024West African journal of medicinePubMeddocument de 9 observations

88 %Outpatient cost constituted approximately 88% of the median monthly economic burden for sickle cell disease patients.

Nigeriadrépanocytosepublié 2022PloS onePubMeddocument de 5 observations

75 %More than 75% of babies born with sickle cell disease each year occur in sub-Saharan Africa.

Nigeriadrépanocytosepublié 2024PloS oneeurope_pmcdocument de 3 observations

679 childrenA total of 679 children with sickle cell anemia were enrolled in two clinical trials.

Nigeriadrépanocytosepublié 2021Pediatric neurologyPubMeddocument de 4 observations

14,7 %The program's 1-year reach for transcranial Doppler screening was 14.7% (4710 out of 32,000) among children with sickle cell anemia in northern Nigeria.

Nigeriadrépanocytosepublié 2022Journal of pediatric hematology/oncologyPubMeddocument de 5 observations

300 000 newborns_per_yearOver 300,000 newborns are diagnosed with sickle cell disease each year globally.

Nigeriadrépanocytosepublié 2020Omics : a journal of integrative biologyeurope_pmc

8,1 yearsThe overall mean age of the 58 patients with sickle cell anemia was 8.1 ± 3.4 years.

Nigeriadrépanocytosepublié 2023Nigerian journal of clinical practicePubMeddocument de 9 observations

1,3 %Among 17 newborns with sickle cell disease (HbSS and HbSC) identified in The Gambia, 2 (1.3%) were from the Wolof ethnic group.

Nigeriadrépanocytosepublié 2024Hemoglobineurope_pmcdocument de 10 observations

-0,05 BMI_z-score_per_unit_food_security_scoreHigher scores on the continuous food security measure, indicating lower food security, were associated with lower BMI z-scores at study entry (β = -0.05, p = 0.047).

Nigeriadrépanocytose · malnutritionpublié 2025Pediatric blood & cancerPubMeddocument de 4 observations

52,8 %The frequency of alpha-thalassemia trait in children with normal transcranial Doppler (TCD) was 52.8% (38/72).

Nigeriadrépanocytosepublié 2021Journal of clinical laboratory analysisPubMed

2,3 %An estimate of 2.3% of the Nigerian population suffer from sickle cell disease.

Nigeriadrépanocytosepublié 2022The Pan African medical journalPubMeddocument de 7 observations

5,9 %The mean Hb F level in 130 SCA subjects was 5.9% with a standard deviation of 3.8%.

Nigeriadrépanocytosepublié 1989African journal of medicine and medical scienceseurope_pmcdocument de 6 observations

91,2 %For HbAA phenotype, isoelectric focusing showed a positive predictive value (PPV) of 91.2%.

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 23 observations

19,38 mg/dlThe SCA group had significantly lowered magnesium levels (19.38 ± 6.37 mg/dl) compared to the HBAA control group (9.65 ± 1.38 mg/dl) with p<0.001.

Nigeriadrépanocytoseobservé 2020-12-02 to 2021-03-31publié 2022The Pan African medical journalPubMeddocument de 4 observations

55,8 %Over half (55.8%) of the male patients with sickle cell disease in Ibadan, Nigeria, had good knowledge of priapism.

Nigeriadrépanocytosepublié 2020West African journal of medicinePubMeddocument de 9 observations

80 %80% of sickle cell anaemia patients in Nigeria had foetal haemoglobin (HbF) values below 8%.

Nigeriadrépanocytosepublié 1990European journal of haematologyeurope_pmcdocument de 5 observations

60 patientsSixty patients with HbSS were recruited.

Nigeriadrépanocytosepublié 2021West African journal of medicinePubMeddocument de 13 observations

2 034 participantsA total of 2,034 participants with or without Sickle Cell Disease were recruited.

Nigeriadrépanocytosepublié 2022Journal of immunoassay & immunochemistryeurope_pmcdocument de 5 observations