Explorer les evidences

515 000 newbornsOver 515,000 newborns are diagnosed with sickle cell disease annually.

Nigeriadrépanocytosepublié 2025BMJ global healtheurope_pmcdocument de 4 observations

36,9 %The most common ECG abnormality seen in children with sickle cell anaemia attending Federal University Teaching Hospital Owerri is left ventricular hypertrophy, observed in 36.9% of the subjects.

Nigeriadrépanocytosepublié 2025BMC pediatricsPubMeddocument de 16 observations

Low level of nitric oxide scavenging (NOS) activity was associated with severe vaso-occlusive crisis in sickle cell anaemia individuals.

Nigeriadrépanocytose · vaso-occlusive crisispublié 2021African health sciencesPubMeddocument de 7 observations

60,9 %The prevalence of hypoxemia in males with SCA was 60.9%.

Nigeriadrépanocytose · hypoxaemiapublié 2024BMC research notesPubMeddocument de 3 observations

24,2 %The level of utilization of hydroxyurea in the treatment of sickle cell disease among care providers in Jos, Nigeria was 24.2%.

Nigeriadrépanocytosepublié 2021African health sciencesPubMeddocument de 5 observations

7,1 per_100_person-yearsThe incidence rates of recurrent strokes were 7.1 per 100 person-years in the low-dose hydroxyurea group.

Nigeriadrépanocytosepublié 2023BloodPubMeddocument de 8 observations

1,34 IU/mLThe mean VWF level in steady state was 1.34 ± 0.23 IU/mL.

Nigeriadrépanocytosepublié 2025Annals of African medicinePubMeddocument de 12 observations

6 %Neurological manifestations were present in half (n = 4) of all recorded deaths, with an overall mortality of 6% in the studied patients.

Nigeriadrépanocytoseobservé March 2022 and February 2025PubMeddocument de 8 observations

17,4 %In 17.4% of encounters, children with sickle cell disease managed by short-term emergency department observation care had their observation care terminated and converted to full admission.

Nigeriadrépanocytoseobservé July 2017 to June 2019publié 2020Transactions of the Royal Society of Tropical Medicine and HygienePubMeddocument de 6 observations

The clinical manifestations of HbSS start between 3 and 5 months of life as a result of reduction in foetal hemoglobin.

Nigeriadrépanocytosepublié 2022Annals of medicinePubMeddocument de 6 observations

26 %Among 164 mothers of children with SCD in a southwestern state of Nigeria, 44 (26%) were undecided about prenatal SCD diagnosis.

Nigeriadrépanocytosepublié 2020TheScientificWorldJournalPubMeddocument de 9 observations

17,9 %The caries experience of children with sickle-cell anaemia was 17.9% in the primary dentition.

Nigeriacaries dentaires · drépanocytosepublié 2025BMC oral healthPubMeddocument de 8 observations

10,6 %10.6% of severe anaemia among children aged 6–59 months in Nigeria was attributable to sickle cell disease.

Nigeriaanémie · drépanocytoseobservé 2018publié 2022BMJ openeurope_pmcdocument de 6 observationsDOI 10.1136/bmjopen-2022-063369

40 %Left ventricular hypertrophy was observed in 18 out of 45 (40.0%) pediatric sickle cell anaemia patients in crisis.

Nigeriadrépanocytoseobservé 2023publié 2025BMC pediatricsPubMeddocument de 16 observations

385 USDAu Nigéria, la drépanocytose constitue un fardeau économique mensuel médian d'environ 385 USD par personne.

NigeriadrépanocytoseHAL · Unilimdocument de 857 observations

65,7 %Among 35 children with moderate sickle cell disease, 23 (65.7%) had ocular abnormalities.

Nigeriadrépanocytosepublié 2021European journal of ophthalmologyPubMeddocument de 3 observations

66,7 %A majority (66.7%) of the sickle cell disease patients had moderate grade anemia.

Nigeriadrépanocytoseobservé 2013 to 2014publié 2022The Pan African medical journalPubMeddocument de 9 observations

59,1 %175 (59.1%) of the caregivers strongly agreed that Newborn Screening for Sickle Cell Disease helps in the early detection and management of Sickle Cell Disease.

Nigeriadrépanocytosepublié 2024Frontiers in public healtheurope_pmcdocument de 8 observations

98,55 %About 98.55% of the 138 newly diagnosed sickle cell disease patients had homozygous sickle-hemoglobin (SS) variant.

Nigeriadrépanocytoseobservé 2013 to 2014publié 2022The Pan African medical journalPubMeddocument de 9 observations

89,9 %After a health education session, approximately 89.9% of pregnant women understood that the chance of conceiving a child with sickle cell disease was 25% for a couple with the sickle cell trait, compared to approximately 23.6% before the session.

Nigeriadrépanocytosepublié 2024BMC pregnancy and childbirthPubMeddocument de 6 observations

1,5 %Sickle cell anaemia affects 1-2% of the population in Sub-Saharan Africa.

Nigeriadrépanocytosepublié 2022Annals of medicinePubMeddocument de 6 observations

50 %Reports have shown that 50 to 80% of affected children in sub-Saharan African countries die annually.

Nigeriadrépanocytosepublié 2022Current stem cell research & therapyeurope_pmcdocument de 2 observations

1,3 %Among young Nigerian SCA patients, asymptomatic gallstones were found in 1.3% of those not in the low-activity UGT1A1 (TA)n genotypes subgroup.

Nigeriadrépanocytosepublié 2019BMC medical geneticsPubMeddocument de 6 observations

15 %The prevalence of A1298C was 15% (29 of 192).

Nigeriadrépanocytosepublié 2019The Pan African medical journalPubMeddocument de 2 observations

36,7 %36.7% of couples were completely unaware of sickle cell phenotypes.

Nigeriadrépanocytosepublié 2025BMC public healthPubMeddocument de 6 observations