Explorer les evidences

108 childrenThe trial included 108 children with sickle cell anemia aged 5–12 years with severe malnutrition.

Nigeriadrépanocytose · malnutritionpublié 2025Nutrition research (New York, N.Y.)PubMeddocument de 6 observations

0,17 Cohen's_dWomen with sickle cell disease had lower utility scores with a small effect size (d = 0.17).

Nigeriadrépanocytosepublié 2019PloS onePubMeddocument de 5 observations

0,9 %CYP2C19 *2/*2 genotype frequency was 0.9% in the SCD group.

Nigeriadrépanocytosepublié 2010Journal of clinical pharmacy and therapeuticseurope_pmcdocument de 10 observations

16,7 %The overall hearing loss prevalence was 16.7% in sickle cell disease patients.

Nigeriadrépanocytosepublié 2025Nigerian journal of clinical practicePubMeddocument de 5 observations

75 %Most of the antibodies (75%) belonged to the Rh blood group system.

Nigeriadrépanocytosepublié 2021ImmunohematologyPubMeddocument de 7 observations

100 %For HbSS phenotype, isoelectric focusing showed 100% specificity, sensitivity, positive predictive value (PPV), and negative predictive value (NPV).

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 23 observations

18,18 metabolic_ratioTwo non-SCD volunteers with metabolic ratios of 18.18 and 25.76 and one SCD patient with a metabolic ratio of 16.77 were classified as poor metabolizers of proguanil.

Nigeriadrépanocytosepublié 2016Pharmacology research & perspectiveseurope_pmcdocument de 5 observations

46,4 %The mutant genotypes MTR 2756 AG/GG were recorded in 46.4% of subjects with disease severity score >7.

Nigeriadrépanocytosepublié 2022West African journal of medicinePubMeddocument de 5 observations

0 %The overall prevalence of primary hypothyroidism among children with sickle cell anaemia in this study was 0%.

Nigeriadrépanocytose · primary hypothyroidismpublié 2023Ethiopian journal of health sciencesPubMeddocument de 7 observations

11,5 %Among 26 alloimmunized sickle cell disease participants, Lewis alloantibodies were observed in 11.5%.

Nigeriadrépanocytosepublié 2025Transfusion and apheresis science : official journal of the World Apheresis Association : europe_pmcdocument de 9 observations

Ventricular dysfunction was more prevalent in the crisis than in the steady state.

Nigeriadrépanocytosepublié 2020Cardiology in the youngPubMeddocument de 6 observations

9,8 %Headaches occurred in 9.8% of the 133 children with sickle cell disease.

Nigeriadrépanocytose · headacheobservé March 2022 and February 2025PubMeddocument de 8 observations

15,4 %15.4% of the participants had good knowledge of SCD.

Nigeriadrépanocytosepublié 2020The Pan African medical journalPubMeddocument de 8 observations

1,3 %1.3% of moderate-to-severe anaemia among children aged 6–59 months in Nigeria was attributable to sickle cell disease.

Nigeriaanémie · drépanocytoseobservé 2018publié 2022BMJ openeurope_pmcdocument de 6 observationsDOI 10.1136/bmjopen-2022-063369

12,8 %Seizures were the most frequent neurological manifestation, occurring in 12.8% of the 133 children with sickle cell disease.

Nigeriadrépanocytose · seizuresobservé March 2022 and February 2025PubMeddocument de 8 observations

27,8 %Among 205 patients with sickle cell disease, 57 (27.8%) had never had a transfusion.

Nigeriadrépanocytosepublié 2025Transfusion and apheresis science : official journal of the World Apheresis Association : europe_pmcdocument de 9 observations

3 malesThree males and two females with sickle cell disease were described among the patients with acute leukaemia.

Nigeriadrépanocytose · leukaemiapublié 2020African health sciencesPubMeddocument de 3 observations

12 folliclesWomen with HbSS had significantly lower median AFC of 12.0 compared to the HbAA group with median AFC of 15.0.

Nigeriadrépanocytosepublié 2026Scientific reportsPubMeddocument de 7 observations

-0,616 correlation_coefficientGlomerular filtration rate was negatively correlated with irreversible percentage sickle cell count (r = -0.616, P = 0.0001).

Nigeriadrépanocytosepublié 2024The Nigerian postgraduate medical journalPubMeddocument de 10 observations

9,4 %The 17 death cases contributed 9.4% (95% CI 5.9 to 14.5) of all sickle cell disease admissions.

Nigeriadrépanocytoseobservé 2012 to 2021publié 2024PloS onePubMeddocument de 12 observations

55,6 %Left ventricular hypertrophy was observed in 10 out of 45 (55.6%) pediatric sickle cell anaemia patients with vaso-occlusive crises.

Nigeriadrépanocytoseobservé 2023publié 2025BMC pediatricsPubMeddocument de 16 observations

503 patientsThe study recruited 503 SCD patients aged ≥15 years from five Nigerian sites.

Nigeriadrépanocytosepublié 2025Gates open researchPubMeddocument de 5 observations

-0,366 correlation_coefficientHopelessness had a modest negative correlation with hemoglobin concentration (r = -0.366, P < 0.001) among clinically stable Nigerian adults with sickle cell disease.

Nigeriadrépanocytosepublié 2020Nigerian journal of clinical practicePubMeddocument de 8 observations

8,06 severity_scoreThe mean SCA severity score was 8.06 ± 3.64, signifying a moderate SCA severity in the study population.

Nigeriadrépanocytoseobservé between September 2018 and March 2019publié 2021African health sciencesPubMeddocument de 3 observations

73,2 %30 (73.2%) of the healthcare workers have recommended Newborn Screening for Sickle Cell Disease to caregivers.

Nigeriadrépanocytosepublié 2024Frontiers in public healtheurope_pmcdocument de 8 observations