Explorer les evidences

20 subjectsGlobin analysis in 30 SCA subjects showed that 20 had four alpha-globin genes, eight had three, and two had two alpha-globin genes.

Nigeriadrépanocytosepublié 1989African journal of medicine and medical scienceseurope_pmcdocument de 6 observations

HbA2 was significantly elevated in HbSS individuals with two alpha gene deletions.

Nigeriaalpha thalassemia · drépanocytosepublié 2022Mediterranean journal of hematology and infectious diseaseseurope_pmcdocument de 17 observationsDOI 10.4084/mjhid.2022.001

95,6 %Among 135 physicians caring for SCD patients in a southwestern state of Nigeria, 129 (95.6%) routinely recommend premarital SCD genetic counseling and testing.

Nigeriadrépanocytosepublié 2020TheScientificWorldJournalPubMeddocument de 9 observations

86 %86% of respondents supported newborn screening for sickle cell disease.

Nigeriadrépanocytosepublié 2018Cureuseurope_pmcdocument de 3 observations

A simplified hydroxyurea dosing strategy achieved high levels of treatment adherence in paediatric sickle cell anaemia patients in South East Nigeria.

Nigeriadrépanocytoseobservé 2022–2024publié 2025BMC pediatricsPubMeddocument de 3 observations

88,9 %Anaemia was prevalent in 88.9% of sickle cell anaemia individuals.

Nigeriadrépanocytosepublié 2021African health sciencesPubMeddocument de 7 observations

4,5 %Hepatitis C infection was observed in 4.5% of the children.

Nigeriadrépanocytose · hépatite Cpublié 2021West African journal of medicinePubMeddocument de 10 observations

90 %90.0% of senior secondary school students in Surulere Local Government Area, Lagos, Nigeria were aware of sickle cell disease.

Nigeriadrépanocytosepublié 2022African journal of primary health care & family medicinePubMeddocument de 11 observations

0,009 p-valueA significantly higher proportion of the cases than the controls had T wave abnormality (p = 0.009).

Nigeriadrépanocytosepublié 2023Ghana medical journalPubMeddocument de 7 observations

26 samplesAn additional 26 samples from a separate sickle cell disease cohort were genotyped.

Nigeriadrépanocytosepublié 2026African journal of laboratory medicineeurope_pmcdocument de 5 observations

Catalase activity was higher in sickle cell anaemia individuals compared to controls.

Nigeriadrépanocytosepublié 2021African health sciencesPubMeddocument de 7 observations

50 %The histological pattern in the 22 patients who had renal biopsies showed mesangioproliferative glomerulonephritis in 11 (50%) patients.

Nigeriadrépanocytose · mesangioproliferative glomerulonephritispublié 2024The Nigerian postgraduate medical journalPubMeddocument de 10 observations

20 %20% of respondents relied on faith when making marital decisions affecting sickle cell disease birth risk.

Nigeriadrépanocytosepublié 2025BMC public healthPubMeddocument de 6 observations

17,6 %The prevalence of alloimmunization in patients with sickle cell disease was 17.6%.

Nigeriadrépanocytosepublié 2025Transfusion and apheresis science : official journal of the World Apheresis Association : europe_pmcdocument de 9 observations

Significantly higher copper levels were observed in sickle cell anaemia patients during vaso-occlusive crisis than in steady clinical state, with a p-value less than 0.001.

Nigeriadrépanocytosepublié 2019African health sciencesPubMeddocument de 6 observations

2,5 %Among 3622 enrolled sickle cell disease patients in Nigeria, 2.5% had experienced stroke.

NigeriaAVC · drépanocytosepublié 2020Blood cells, molecules & diseaseseurope_pmcdocument de 16 observations

5,9 %The mean foetal haemoglobin (HbF) level in sickle cell anaemia patients in Nigeria was 5.9% with a standard deviation of 3.8%.

Nigeriadrépanocytosepublié 1990European journal of haematologyeurope_pmcdocument de 5 observations

97 %Two hundred and ninety (97%) of the caregivers expressed willingness to participate in the Newborn Screening for Sickle Cell Disease.

Nigeriadrépanocytosepublié 2024Frontiers in public healtheurope_pmcdocument de 8 observations

3,35 odds_ratioIn multivariate analysis, neuralgic pain was associated with painful crisis with an odds ratio of 3.35.

NigeriadrépanocytosePubMeddocument de 10 observations

180 ng/mlThe median serum ferritin level of children with sickle cell disease was 180.00 ng/ml with an interquartile range of 237.50 ng/ml.

Nigeriadrépanocytosepublié 2023West African journal of medicinePubMeddocument de 8 observations

0,351 correlation_coefficientHopelessness had a modest positive correlation with anxiety (r = 0.351, P < 0.001) among clinically stable Nigerian adults with sickle cell disease.

Nigeriadrépanocytosepublié 2020Nigerian journal of clinical practicePubMeddocument de 8 observations

2,5 %Nigeria has 2–3% of its population affected by sickle cell disease.

NigeriadrépanocytosePubMeddocument de 7 observations

42,3 %Left ventricular hypertrophy was observed in 42.3% of pediatric sickle cell anaemia patients with severe anaemia.

Nigeriadrépanocytoseobservé 2023publié 2025BMC pediatricsPubMeddocument de 16 observations

6,3 %Among 3622 enrolled sickle cell disease patients in Nigeria, 6.3% had renal complications.

Nigeriadrépanocytose · renal complicationspublié 2020Blood cells, molecules & diseaseseurope_pmcdocument de 16 observations

31,8 %The incidence of bacterial infection in hospitalized children with sickle cell anaemia was 31.8%.

Nigeriadrépanocytosepublié 2021The Nigerian postgraduate medical journalPubMeddocument de 8 observations