Explorer les evidences

-0,336 correlation_coefficientGlomerular filtration rate was negatively correlated with fractional excretion of sodium (r = -0.336, P = 0.004).

Nigeriadrépanocytosepublié 2024The Nigerian postgraduate medical journalPubMeddocument de 10 observations

1 %Hydroxyurea utilization among Sickle Cell Disease patients in Sub-Saharan Africa stands at less than 1%.

Nigeriadrépanocytosepublié 2025PloS oneeurope_pmcdocument de 2 observations

53 %For HbAS phenotype, isoelectric focusing showed a positive predictive value (PPV) of 53%.

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 23 observations

25,5 %The prevalence of pulmonary hypertension among children with sickle cell anaemia was 25.5%.

Nigeriadrépanocytose · pulmonary hypertensionpublié 2020BMC pediatricsPubMeddocument de 8 observations

Sickle cell anaemia participants had lower mean values of Total Cholesterol (TC), High Density Lipoprotein (HDL), and Low Density Lipoprotein (LDL) than controls, with p < 0.05.

Nigeriadrépanocytosepublié 2019The Pan African medical journalPubMeddocument de 4 observations

61 %Among 138 newly diagnosed sickle cell disease patients, 61% (1% SCD prevalence) were in the pediatric age-group.

Nigeriadrépanocytoseobservé 2013 to 2014publié 2022The Pan African medical journalPubMeddocument de 9 observations

Alpha thalassaemia deletion significantly reduces the transfusion requirements of patients with sickle-cell anaemia.

Nigeriadrépanocytosepublié 1994European journal of haematologyeurope_pmcdocument de 2 observations

-3,7 z-scoreChildren with sickle cell anemia and severe malnutrition had a mean baseline BMI z-score of -3.7.

Nigeriadrépanocytose · malnutritionpublié 2025Nutrition research (New York, N.Y.)PubMeddocument de 6 observations

0,2 %Among 1,168 newborn babies screened in The Gambia from April 14 to August 12, 2023, two (0.2%) had heterozygous HbS and HbC (HbSC).

Nigeriadrépanocytoseobservé April 14 to August 12, 2023publié 2024Hemoglobineurope_pmcdocument de 10 observations

38,9 %Left ventricular hypertrophy was observed in 7 out of 45 (38.9%) pediatric sickle cell anaemia patients with hyperhemolytic crises.

Nigeriadrépanocytoseobservé 2023publié 2025BMC pediatricsPubMeddocument de 16 observations

Serum zinc level was lower in sickle cell anaemia patients than in controls, with a p-value less than 0.001.

Nigeriadrépanocytosepublié 2019African health sciencesPubMeddocument de 6 observations

A significantly different value (p < 0.05) was observed between number of transfusions per year and alpha globin gene status in 28 patients with sickle-cell anaemia.

Nigeriadrépanocytosepublié 1994European journal of haematologyeurope_pmcdocument de 2 observations

0,018 p-valueA significantly higher proportion of the cases than the controls had heart blocks (p = 0.018).

Nigeriadrépanocytosepublié 2023Ghana medical journalPubMeddocument de 7 observations

67,6 %For HbAA phenotype, isoelectric focusing showed a specificity of 67.6%.

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 23 observations

3 %Cholecystitis was observed in 3.0% of the children.

Nigeriacholecystitis · drépanocytosepublié 2021West African journal of medicinePubMeddocument de 10 observations

The average serum magnesium was higher in the group with moderate to severe pain during vaso-occlusive crisis, but the difference was not statistically significant across the three pain severity groups (p = 0.315).

Nigeriadrépanocytosepublié 2025BMC pediatricsPubMeddocument de 3 observations

84,7 %For HbAA phenotype, isoelectric focusing showed a sensitivity of 84.7%.

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 23 observations

2 femalesTwo females with sickle cell disease were described among the patients with acute leukaemia.

Nigeriadrépanocytose · leukaemiapublié 2020African health sciencesPubMeddocument de 3 observations

84,6 %318 (84.6%) of the participants had fewer hospital admissions while using hydroxyurea.

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 10 observations

98,1 %The fractional excretion of sodium was elevated in 98.1% of patients with sickle cell disease.

Nigeriadrépanocytosepublié 2024The Nigerian postgraduate medical journalPubMeddocument de 10 observations

56,4 %Among male patients with sickle cell disease in Ibadan, Nigeria, who experienced priapism, fear of recurrence was reported by 56.4%.

Nigeriadrépanocytosepublié 2020West African journal of medicinePubMeddocument de 9 observations

23 patients23 had other complications.

Nigeriadrépanocytosepublié 2021Hematology (Amsterdam, Netherlands)PubMeddocument de 16 observations

71,6 %561 (71.6%) of the 780 mothers agreed that sickle cell disease can be ameliorated by newborn screening.

Nigeriadrépanocytosepublié 2023West African journal of medicinePubMeddocument de 5 observations

6,9 %The prevalence of HbSS α+2 was 6.9% among sickle cell disease patients.

Nigeriadrépanocytose · HbSS α+2publié 2022Mediterranean journal of hematology and infectious diseaseseurope_pmcdocument de 17 observationsDOI 10.4084/mjhid.2022.001

607 U/LThe median serum lactate dehydrogenase level was 607.0 U/L with an interquartile range of 487.3–758.5 U/L.

Nigeriadrépanocytosepublié 2023West African journal of medicinePubMeddocument de 7 observations