Explorer les evidences

476 womenOf 619 screened pregnant women with HbSS and HbSC, 476 eligible women were recruited into a randomized controlled trial in southwest Nigeria.

Nigeriadrépanocytoseobservé July 1, 2020 to May 27, 2024publié 2026The Lancet. Global healthPubMeddocument de 13 observations

0 %CAE had a sensitivity of 0% for identifying the AC genotype relative to PCR.

Nigeriadrépanocytosepublié 2021Global pediatric healtheurope_pmcdocument de 5 observations

13 403 patientsThe SickleInAfrica consortium registry enrolled 13,403 sickle cell disease patients from 2017 to 2021 across 31 facilities in Ghana, Nigeria, and Tanzania.

Ghana · Nigeria · Tanzaniedrépanocytoseobservé 2017-2021publié 2025EJHaemeurope_pmcdocument de 7 observations

1 %The prevalence of sickle cell disease among the pediatric age-group was 1%.

Nigeriadrépanocytoseobservé 2013 to 2014publié 2022The Pan African medical journalPubMeddocument de 9 observations

5,6 %Left ventricular hypertrophy was observed in 1 out of 45 (5.6%) pediatric sickle cell anaemia patients with sequestration crises.

Nigeriadrépanocytoseobservé 2023publié 2025BMC pediatricsPubMeddocument de 16 observations

88,89 %88.89% of sickle cell anaemia patients screened using Natriuretic peptide were at risk of developing pulmonary hypertension (NT-proBNP levels ≥ 160 pg/ml).

Nigeriadrépanocytosepublié 2022West African journal of medicinePubMeddocument de 8 observations

25,6 %Only 25.6% of study participants knew about the positive role of community engagement and education in reducing the prevalence of sickle cell disease and alleviating sickle cell disease crises.

Nigeriadrépanocytosepublié 2023Frontiers in geneticseurope_pmcdocument de 5 observationsDOI 10.3389/fgene.2023.1052444

100 %The sensitivity and specificity for SS, SC, AS, AC, and AA genotypes by HemotypeSC relative to PCR were each 100%.

Nigeriadrépanocytosepublié 2021Global pediatric healtheurope_pmcdocument de 5 observations

5,9 %Asymptomatic gallstones were found in 5.9% of young Nigerian SCA patients.

Nigeriadrépanocytosepublié 2019BMC medical geneticsPubMeddocument de 6 observations

7 %Sickle cell disease contributes up to 7% to 16% of under-five mortality in African countries.

Nigeriadrépanocytosepublié 2025Communications medicineeurope_pmcdocument de 4 observations

7 256 casesOf the 72,333 paediatric admissions, 7,256 (10.0%) had sickle cell disease.

Nigeriadrépanocytoseobservé 2012 to 2021publié 2024PloS onePubMeddocument de 12 observations

97 %The common haplotype (- - - - + + - +) was present in 97% of the beta s chromosomes examined in sickle cell anaemia patients in Nigeria.

Nigeriadrépanocytosepublié 1990European journal of haematologyeurope_pmcdocument de 5 observations

150 000 cases_per_yearIn Nigeria, about 150000 babies are born annually with sickle cell disease (SCD).

Nigeriadrépanocytosepublié 2020PloS onePubMeddocument de 4 observations

-0,274 correlation_coefficientZinc correlated inversely with disease severity scores in sickle cell anaemia patients, with a Spearman correlation coefficient of -0.2743 and a p-value of 0.006.

Nigeriadrépanocytosepublié 2019African health sciencesPubMeddocument de 6 observations

HSP 70 levels were significantly increased (P<0.005) in sickle cell disease subjects with HbSS and HbSC genotypes in both steady state and crisis compared to controls with HbAA and HbAS genotypes.

Nigeriadrépanocytosepublié 2022The Pan African medical journalPubMeddocument de 14 observations

94 %94% of sickle cell anaemia patients in Nigeria had foetal haemoglobin (HbF) levels below 10%.

Nigeriadrépanocytosepublié 1990European journal of haematologyeurope_pmcdocument de 5 observations

63 %63.0% of senior secondary school students in Surulere Local Government Area, Lagos, Nigeria had good knowledge of sickle cell disease.

Nigeriadrépanocytosepublié 2022African journal of primary health care & family medicinePubMeddocument de 11 observations

52,9 %Among 3622 enrolled sickle cell disease patients in Nigeria, 1889 (52.9%) were females.

Nigeriadrépanocytosepublié 2020Blood cells, molecules & diseaseseurope_pmcdocument de 16 observations

386,4 cells/μLAbsolute neutrophil count in steady state subjects was 386.4 ± 31.

Nigeriadrépanocytosepublié 2022The Pan African medical journalPubMeddocument de 14 observations

-0,07 BMI_z-score_per_unit_food_security_scoreHigher scores on the continuous food security measure, indicating lower food security, were associated with lower BMI z-scores after malnutrition treatment (β = -0.07, p = 0.016).

Nigeriadrépanocytose · malnutritionpublié 2025Pediatric blood & cancerPubMeddocument de 4 observations

26 %Isoelectric focusing (IEF) tests identified 133 (26.0%) HbAS phenotypes among 511 newborns.

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 23 observations

13,6 %The prevalence of cholelithiasis in pediatric sickle cell disease in Lagos was 13.6%.

Nigeriacholelithiasis · drépanocytosepublié 2022Annals of African medicinePubMeddocument de 6 observations

0,49 z_scoreAt the end of the trial, the mean change in body mass index z score was 0.49.

Nigeriadrépanocytosepublié 2023Blood advancesPubMeddocument de 6 observations

8,7 %The prevalence of overt stroke among SCD patients in Nigeria was 8.7%.

NigeriaAVC · drépanocytosepublié 2015Cardiovascular journal of Africaeurope_pmcdocument de 2 observationsDOI 10.5830/cvja-2015-040

0,001 p-valueOverweight/obesity in sickle cell anemia was significantly associated with upper social class (P = 0.001).

Nigeriadrépanocytose · overweight/obesitypublié 2020Nigerian journal of clinical practicePubMeddocument de 9 observations