Explorer les evidences

96,3 %A high proportion of children with sickle cell disease (96.3%) had low haemoglobin status compared with controls (56.9%).

Nigeriadrépanocytosepublié 2023West African journal of medicinePubMeddocument de 8 observations

99,9 %99.9% (10,167/10,168) of pregnant women who received education on SCD accepted and completed the survey, had blood drawn for haemoglobin electrophoresis and received their results.

Nigeriadrépanocytosepublié 2021BMC pregnancy and childbirtheurope_pmcdocument de 4 observationsDOI 10.1186/s12884-021-03974-4

2,3 odds_ratioWasting was independently associated with increased risk of restrictive spirometry (OR 2.3, 95% CI 1.1 to 5.0).

Nigeriadrépanocytosepublié 2019ThoraxPubMeddocument de 7 observations

7 %7.0% of the children with sickle cell anaemia had high TSH value.

Nigeriadrépanocytose · hypothyroidismpublié 2023Ethiopian journal of health sciencesPubMeddocument de 7 observations

5,9 %Among 3622 enrolled sickle cell disease patients in Nigeria, 5.9% had experienced acute chest syndrome.

Nigeriadrépanocytose · syndrome thoracique aigu (drépanocytose)publié 2020Blood cells, molecules & diseaseseurope_pmcdocument de 16 observations

Sickle cell anaemia participants had higher mean values of triglycerides (TG) and Very Low Density Lipoprotein (VLDL) than controls, with p < 0.05.

Nigeriadrépanocytosepublié 2019The Pan African medical journalPubMeddocument de 4 observations

65 %65% of the interviewed students had a positive attitude towards sickle cell disease.

Nigeriadrépanocytosepublié 2021The Pan African medical journalPubMeddocument de 7 observations

2 947 patientsNorth Central registered 2,947 patients with sickle cell disease, representing 37.9% of the total enrolled in Nigeria.

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 8 observations

73,3 %ECG abnormalities were recorded in 33 out of 45 (73.3%) pediatric sickle cell anaemia patients in crisis.

Nigeriadrépanocytoseobservé 2023publié 2025BMC pediatricsPubMeddocument de 16 observations

78,7 %78.7% of patients with sickle cell disease reside in sub-Saharan Africa.

Nigeriadrépanocytosepublié 2025BMJ global healtheurope_pmcdocument de 4 observations

24,4 %24.4% of senior secondary school students in Surulere Local Government Area, Lagos, Nigeria knew about prevention of sickle cell disease by genetic counselling.

Nigeriadrépanocytosepublié 2022African journal of primary health care & family medicinePubMeddocument de 11 observations

3,8 %Among the 743 respondents who tested, 28 (3.8%) had HbSS phenotype.

Nigeriadrépanocytosepublié 2025West African journal of medicinePubMeddocument de 8 observations

A significantly higher proportion of respondents in type SS group had abnormal left ventricular systolic and diastolic dysfunction when compared with those in type AA group.

Nigeriadrépanocytosepublié 2021Malawi medical journal : the journal of Medical Association of MalawiPubMeddocument de 3 observations

6 %Among those screened, 6.0% (281 out of 4710) had abnormal transcranial Doppler velocities (≥200 cm/s).

Nigeriadrépanocytosepublié 2022Journal of pediatric hematology/oncologyPubMeddocument de 5 observations

1 027 patientsSouth East registered 1,027 patients with sickle cell disease, representing 13.2% of the total enrolled in Nigeria.

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 8 observations

84,69 beats/minuteSickle cell patients had faster pulse rates (84.69 ± 9.48 vs 75.48 ± 10.35 beats/minute, p=0.000).

Nigeriadrépanocytosepublié 2022West African journal of medicinePubMeddocument de 8 observations

18,6 cm²Post-intervention ulcer size ranged from 0.0 cm² to 272 cm², with a median of 18.6 cm², and the change was statistically significant (p = 0.02).

Nigeriadrépanocytoseobservé 2015publié 2020African journal of laboratory medicineeurope_pmcdocument de 3 observations

29,5 %29.5% of orthopaedic surgeons surveyed had used the tourniquet in patients with sickle cell disease.

Nigeriadrépanocytosepublié 2021The Nigerian postgraduate medical journalPubMeddocument de 8 observations

5 recurrent_strokesA total of 5 recurrent strokes occurred in the moderate-dose hydroxyurea group.

Nigeriadrépanocytosepublié 2023BloodPubMeddocument de 8 observations

13,2 %Among 3622 enrolled sickle cell disease patients in Nigeria, 13.2% had been hospitalized.

Nigeriadrépanocytosepublié 2020Blood cells, molecules & diseaseseurope_pmcdocument de 16 observations

-0,448 correlation_coefficientGlomerular filtration rate was negatively correlated with fractional excretion of potassium (r = -0.448, P = 0.0001).

Nigeriadrépanocytosepublié 2024The Nigerian postgraduate medical journalPubMeddocument de 10 observations

4 %In the phase 2 portion of the RISE UP trial, the haemoglobin response rate (≥1.0 g/dL increase from baseline in average haemoglobin concentration from week 10 through week 12) was 4% in the placebo group.

Nigeriadrépanocytosepublié 2025The Lancet. Haematologyeurope_pmcdocument de 9 observations

0 %The overall prevalence of secondary hypothyroidism among children with sickle cell anaemia in this study was 0%.

Nigeriadrépanocytose · secondary hypothyroidismpublié 2023Ethiopian journal of health sciencesPubMeddocument de 7 observations

31,1 %In the study, 31.1% of children with sickle cell anaemia presented with bone pain.

Nigeriadrépanocytosepublié 2024West African journal of medicinePubMeddocument de 9 observations

4 %The median reticulocyte count was 4.0% with an interquartile range of 3.0–8.4%.

Nigeriadrépanocytosepublié 2023West African journal of medicinePubMeddocument de 7 observations