Explorer les evidences

14,7 yearsThe mean age at menarche was 14.7 years in girls with sickle cell anaemia.

Nigeriadrépanocytosepublié 2023West African journal of medicinePubMeddocument de 7 observations

14,4 %More than one-tenth of the sample (14.4%) indicated that they would marry someone with sickle cell disease irrespective of their own genotype.

Nigeriadrépanocytosepublié 2022Hematology (Amsterdam, Netherlands)PubMeddocument de 6 observations

10,6 %32 (10.6%) of the caregivers indicated reluctance to accept positive results of Sickle Cell Disease from Newborn Screening.

Nigeriadrépanocytosepublié 2024Frontiers in public healtheurope_pmcdocument de 8 observations

54,1 %A majority (54.1%) of the SCA patients had mild disease, while 35.3% and 10.6% had moderate and severe disease, respectively.

Nigeriadrépanocytosepublié 2023Malawi medical journal : the journal of Medical Association of MalawiPubMeddocument de 12 observations

73,5 %An ischaemic ECG was observed in 25 (73.5%) SCA children during VOC.

Nigeriadrépanocytosepublié 2020Paediatrics and international child healtheurope_pmcdocument de 8 observations

100 %The diagnostic sensitivity of SickleSCAN™ for sickle cell disease (Hb SS and Hb SC) was 100.0%.

Nigeriadrépanocytosepublié 2017Hemoglobineurope_pmcdocument de 5 observations

8,5 %8.5% of the children with sickle cell anaemia had high free T3.

Nigeriadrépanocytose · hypothyroidismpublié 2023Ethiopian journal of health sciencesPubMeddocument de 7 observations

1,3 %Among 1,168 newborn babies screened in The Gambia from April 14 to August 12, 2023, 15 (1.3%) had homozygous HbS (HbSS).

Nigeriadrépanocytoseobservé April 14 to August 12, 2023publié 2024Hemoglobineurope_pmcdocument de 10 observations

74,5 %In the study, 74.5% of children with sickle cell anaemia had previous hospital admission.

Nigeriadrépanocytosepublié 2024West African journal of medicinePubMeddocument de 9 observations

312 000 births_per_yearMore than 312,000 births are affected annually by sickle cell anaemia.

Nigeriadrépanocytosepublié 2019Blood cells, molecules & diseaseseurope_pmcdocument de 5 observations

Sickle cell disease is a major cause of mortality and morbidity in Nigeria.

Nigeriadrépanocytosepublié 2022The Pan African medical journalPubMeddocument de 14 observations

20 %Among young Nigerian SCA patients, asymptomatic gallstones were significantly more prevalent in the low-activity UGT1A1 (TA)n genotypes subgroup (20%) compared to other subgroups (1.3%), with p = 0.0033.

Nigeriadrépanocytosepublié 2019BMC medical geneticsPubMeddocument de 6 observations

65,1 %Among 135 physicians caring for SCD patients in a southwestern state of Nigeria, 89 (65.1%) were aware of the national government newborn screening program.

Nigeriadrépanocytosepublié 2020TheScientificWorldJournalPubMeddocument de 9 observations

-0,483 correlation_coefficientHopelessness had a modest negative correlation with resilience (r = -0.483, P < 0.001) among clinically stable Nigerian adults with sickle cell disease.

Nigeriadrépanocytosepublié 2020Nigerian journal of clinical practicePubMeddocument de 8 observations

2,1 %The proportion of sickle cell disease cases from total admissions ranged from 2.1% to 16.3% across the ten tertiary health facilities.

Nigeriadrépanocytoseobservé 2012 to 2021publié 2024PloS onePubMeddocument de 12 observations

1 %Isoelectric focusing (IEF) tests identified 5 (1.0%) HbSS phenotypes among 511 newborns.

Nigeriadrépanocytosepublié 2022Frontiers in geneticseurope_pmcdocument de 23 observations

490 per_1000The estimated national average under-5 mortality for children with sickle cell disease born between 2003 and 2013 in Nigeria was 490 per 1000 livebirths.

Nigeriadrépanocytoseobservé 2003–2013publié 2021The Lancet. Haematologyeurope_pmcdocument de 6 observations

6,5 %Among 3622 enrolled sickle cell disease patients in Nigeria, 6.5% had leg ulcers.

Nigeriadrépanocytose · leg ulcerspublié 2020Blood cells, molecules & diseaseseurope_pmcdocument de 16 observations

0,44 µg/LThe mean ADAMTS13 level in steady state was 0.44 ± 0.06 µg/L.

Nigeriadrépanocytosepublié 2025Annals of African medicinePubMeddocument de 12 observations

Serum levels of vitamin D, calcium, CAT, SOD, GPX and GST were significantly lower in the SCA group compared to the control group.

Nigeriadrépanocytosepublié 2025Sultan Qaboos University medical journalPubMeddocument de 5 observations

The frequency of testicular pain (p = 0.04), weight (p = 0.02) and pubic hair rating (p = 0.03) of the HbSS participants were significant predictors of increased testicular volumes in the HbSS participants, irrespective of pubertal status.

Nigeriadrépanocytosepublié 2021Journal of tropical pediatricsPubMeddocument de 2 observations

0,4 z-scoreChildren with sickle cell anemia without an enrolled sibling had a mean BMI z-score change of 0.4.

Nigeriadrépanocytosepublié 2025Nutrition research (New York, N.Y.)PubMeddocument de 6 observations

89 patientsEighty-nine out of 116 patients had laboratory analysis.

Nigeriadrépanocytosepublié 2021Pediatric blood & cancereurope_pmcdocument de 10 observations

96,7 %Of 122 children with sickle cell disease admitted to the emergency department for painful crises from July 2017 to June 2019, 118 (96.7%) with 167 hospital visits were managed by short-term emergency department observation care.

Nigeriadrépanocytoseobservé July 2017 to June 2019publié 2020Transactions of the Royal Society of Tropical Medicine and HygienePubMeddocument de 6 observations

27,3 %The histological pattern in the 22 patients who had renal biopsies showed minimal change disease in 6 (27.3%) patients.

Nigeriadrépanocytose · minimal change diseasepublié 2024The Nigerian postgraduate medical journalPubMeddocument de 10 observations