Explorer les evidences

70 %Early neonatal diagnosis combined with affordable care can prevent up to 70% of SCD-related deaths.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

349 cases349 out of 612 sickle cell disease patients had extracardiac organ damages including stroke, leg ulcer, priapism, microalbuminuria or osteonecrosis in Cameroon, Mali, and Senegal.

Cameroun · Mali · SénégaldrépanocytoseHAL · Unilimdocument de 2 observations

78,33 %HemotypeSC® had a sensitivity of 78.33% (95% CI: 67.91–88.76) to detect sickle cell disease.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

96,1 %Of 4333 delivering women, 4164 (96.1%) were offered sickle cell disease newborn screening (SCD NBS).

Malidrépanocytoseobservé 21 April to 17 August 2021HAL · Unilimdocument de 103 observations

50 %Sickle cell disease is associated with a high mortality of 50%–80% before 5 years of age without care management.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

98,66 %HemotypeSC® had a negative predictive value (NPV) of 98.66% (95% CI: 98.24–99.03) to detect sickle cell disease carrier status.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

95,22 %HemotypeSC® had a sensitivity of 95.22% [95% CI: 93.74–96.70] for diagnosing possible sickle cell disease (SCD) compared to high-performance liquid chromatography in a study in Mali, April–August 2021.

Malidrépanocytoseobservé April–August 2021HAL · Unilimdocument de 103 observations

2 583 individualsThe study included 2583 SCD patients and healthy controls aged 5–21 years old in Mali, Senegal, Cameroon, Gabon and the Ivory Coast.

Cameroun · Côte d'Ivoire · Gabon · Mali · Sénégaldrépanocytosepublié 2019British journal of haematologyeurope_pmcdocument de 6 observations

63,9 %63.9% of mothers did not know the complications of sickle cell disease.

Malidrépanocytosepublié 2009Мир науки, культуры, образованияOpenAlexdocument de 12 observations

1 per_60One out of 60 sickle cell disease cases was missed by each rapid diagnostic test.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

79,66 %The positive predictive value (PPV) of HemotypeSC® for detecting sickle cell disease was 79.66% (95% CI: 69.39–89.93).

MalidrépanocytoseHAL · Unilimdocument de 103 observations

2 %Sickle cell disease is most prevalent in sub-Saharan Africa, affecting approximately 2% of the population in Mali.

Malidrépanocytosepublié 2024Hemoglobineurope_pmcdocument de 9 observations

0,63 %The prevalence of HbSS among 3648 newborns in Mali was 0.63% (95% CI: 0.40–0.94).

Malidrépanocytoseobservé April–August 2021HAL · Unilimdocument de 103 observations

15,2 %15.2% of mothers stated they would have recourse to a traditional practitioner in front of a sickle cell disease crisis.

Malidrépanocytosepublié 2009Мир науки, культуры, образованияOpenAlexdocument de 12 observations

93,57 %HemotypeSC® had a positive predictive value (PPV) of 93.57% (95% CI: 91.88–95.26) to detect sickle cell disease carrier status.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

3 %Homozygote form prevalence of sickle cell disease in Mali is 3%.

Malidrépanocytosepublié 2009Мир науки, культуры, образованияOpenAlexdocument de 12 observations

3 627 patientsThe CADRE study included 3627 patients with sickle cell disease and 943 healthy controls.

Cameroun · Côte d'Ivoire · Gabon · Mali · Sénégaldrépanocytosepublié 2016CirculationPubMeddocument de 5 observations

SCD children under 9 years old were more susceptible to cerebral vasculopathy complications than those aged 9 years and older.

Malicerebral vasculopathy · drépanocytosepublié 2013BloodOpenAlexdocument de 10 observations

58,3 %58.3% of mothers stated they would resort to a medical structure first in the event of discovered sickle cell disease.

Malidrépanocytosepublié 2009Мир науки, культуры, образованияOpenAlexdocument de 12 observations

3 699 patientsThe study involved 3699 sickle cell disease patients living in Mali, Senegal, Ivory Coast, Democratic Republic of Congo, Gabon and Cameroon.

Cameroun · Côte d'Ivoire · Gabon · Mali · Sénégaldrépanocytosepublié 2024British journal of haematologyeurope_pmcdocument de 10 observations

3 timesDans la population sénégalaise, la proportion de patients présentant une TRJV élevée est trois fois plus forte que dans la population malienne.

Mali · SénégaldrépanocytoseHAL · Unilimdocument de 202 observations

50 %Half of the true mis-identified sickle cell disease cases were related to the β-plus-thalassaemia allele.

Malidrépanocytose · β-plus-thalassaemiaHAL · Unilimdocument de 103 observations

1 per_100Au Mali, le taux de mortalité des enfants drépanocytaires de moins de 5 ans sous suivi médical a été réduit à moins de 1 %.

MalidrépanocytoseHAL · Unilimdocument de 857 observations

56 %56% of mothers stated they would have recourse to modern medicine in front of a sickle cell disease crisis.

Malidrépanocytosepublié 2009Мир науки, культуры, образованияOpenAlexdocument de 12 observations

6,1 %Au Mali, la fréquence du trait drépanocytaire varie de 6,1 % dans les régions du nord à 15 à 20 % dans certaines régions du sud.

MalidrépanocytoseHAL · Unilimdocument de 202 observations