Explorer les evidences

90 %Plasmodium falciparum malaria cases in Africa represent over 90% of the global burden.

Malipaludismepublié 2022Frontiers in geneticseurope_pmcdocument de 5 observations

97,3 %P. falciparum was the most predominant species, accounting for 97.3% of Plasmodium-positive samples.

Malipaludismepublié 2023Performance of Rapid Diagnostic Tests for Malaria Diagnosis in Malieurope_pmcdocument de 3 observationsDOI 10.20944/preprints202311.1579.v1

0,26 per_hourThe parasite clearance rate constant was 0.26 per hour for dihydroartemisinin-piperaquine.

Malipaludismepublié 2018Malaria journaleurope_pmcdocument de 9 observations

94,9 %Crude ACPRs were 94.9% for SP + AS, 98.6% for SP + AQ, and 93.5% for SP alone in the treatment of uncomplicated P. falciparum malaria in Mali.

Malipaludismepublié 2015Malaria journaleurope_pmcdocument de 7 observations

36 health_districtsAn additional 36 health districts in Mali will receive the malaria vaccine in 2026.

Malipaludismeobservé 2026HAL · Unilimdocument de 95 observations

88,2 %In a phase 2 trial in Mali, the efficacy of 40 mg of CIS43LS per kilogram as compared with placebo against Plasmodium falciparum infection was 88.2% at 6 months.

Malipaludismepublié 2022The New England journal of medicineeurope_pmcdocument de 5 observations

0,48 SIRDeployment of mobile health teams led to a standardized incidence ratio of 0.48 for malaria morbidity in Kidal, Mali.

MalipaludismeHAL · Unilimdocument de 80 observations

MSP-1(42) antibody levels were significantly higher in malaria vaccine recipients after the second immunization relative to baseline and to the control group.

Malipaludismepublié 2006PLoS clinical trialseurope_pmcdocument de 2 observations

12,2 per_1000_person_yearsThe lowest malaria incidence was 12.2 cases per 1,000 person-years in the health district of Al-Ourche (Taoudenni region in the north) in the year 2017–2018.

Malipaludismeobservé 2017–2018HAL · Unilimdocument de 111 observations

1 014 casesThe malaria outbreak peaked in week 39 with 1,014 cases in the Kidal region.

MalipaludismeHAL · Unilimdocument de 80 observations

1,5 %P. malariae prevalence was 1.50% in passive screening.

Malipaludismepublié 2023Tropical medicine and infectious diseaseeurope_pmcdocument de 16 observations

30 %The mean proportion of severe malaria cases reported between 2017 and 2022 was 30% in Mali.

Malipaludismeobservé 2017–2022HAL · Unilimdocument de 111 observations

5,04 per_1000_person_weeksFrom May 2024 to February 2025, children aged 0–11 months had 5.04 uncomplicated malaria cases per 1,000 person-weeks in the Kidal region.

Malipaludismeobservé 2024-2025HAL · Unilimdocument de 80 observations

71 %In the non-SMC patient population, 220 out of 310 (71%) samples were successfully PCR analyzed in November 2014.

Malipaludismeobservé November 2014publié 2016PloS oneeurope_pmcdocument de 4 observations

0,25 ORSeasonal malaria chemoprevention conveyed a significant protective effect against clinical malaria with an odds ratio of 0.25 in 2012 and 2014 in Koutiala, Mali.

Malipaludismepublié 2020International journal of environmental research and public healtheurope_pmcdocument de 7 observationsDOI 10.3390/ijerph17186639

150 per_1000_person-yearsMalaria incidence in Mali went from 150 to 172 per 1000 person-years between 2021 and 2022.

Malipaludismeobservé 2021HAL · Unilimdocument de 111 observations

38,5 daysSulfadoxine-pyrimethamine treatment delayed the median time to first clinical malaria episode from 38.5 to 68 days.

Malipaludismepublié 2002The American journal of tropical medicine and hygieneeurope_pmcdocument de 4 observationsDOI 10.4269/ajtmh.2002.67.604

23 %The proportion of gametocyte carriers declined from 23% at baseline to 6% on day 21 in the 2010–2011 study.

Malipaludismeobservé 2010-2011publié 2016Parasite (Paris, France)europe_pmcdocument de 5 observationsDOI 10.1051/parasite/2016003

3,24 %La prévalence globale des gamétocytes variait d’un mois à l’autre selon l’année, avec une prévalence moyenne de 3,24 % dans le dépistage passif.

MalipaludismeHAL · Unilimdocument de 214 observations

606 patientsA total of 606 patients were enrolled in the clinical trial, with 303 in each treatment arm.

Malipaludismeobservé 2003 and 2004publié 2006The American journal of tropical medicine and hygieneeurope_pmcdocument de 4 observationsDOI 10.4269/ajtmh.2006.75.630

56 %In Mali, seasonal malaria chemoprevention reduced severe malaria by 56% with a relative risk of 0.44 and 95% confidence interval 0.22–0.91.

MalipaludismeHAL · Unilimdocument de 110 observations

18 out_of_21Among AMA1 recipients, 18/21 evaluable samples stimulated with AMA1 demonstrated increased IFN-γ, TNF-α, and IL-2 derived from CD4(+) T cells by day 150 compared to 0/10 in the control group.

Malipaludismepublié 2016Vaccineeurope_pmcdocument de 2 observations

100 per_1000_person_yearsDistricts with incidence rates between 100 and 250 cases per 1,000 person-years or Pf/Pv prevalence between 1% and 10% were classified as 'Low Transmission Zones'.

Malipaludisme · Pf/PvHAL · Unilimdocument de 95 observations

1,688 per_1000_person_weeksThe malaria epidemic in Kidal, Mali began in week 30, peaked in week 39 with 1,014 cases, and lasted for 28 weeks, with 1.688 cases per 1,000 person-weeks.

MalipaludismeHAL · Unilimdocument de 80 observations

0,62 per_1000_person_weeksFrom May 2024 to February 2025, children aged 5–14 years had 0.62 uncomplicated malaria cases per 1,000 person-weeks in the Kidal region.

Malipaludismeobservé 2024-2025HAL · Unilimdocument de 80 observations