Explorer les evidences

25 per_100000Entre 2000 et 2019, le nombre de décès associés au paludisme est passé de 25 à 10 pour 100 000 personnes exposées au risque.

Malipaludismeobservé 2000 à 2019HAL · Unilimdocument de 214 observations

0 p-valueIn Mali, a retrospective study conducted at CHU Gabriel Touré in Bamako between 2014 and 2018 reported a significant drop in case fatality (p = 0.0001) for cerebral malaria after SMC introduction.

Malipaludismeobservé 2014–2018HAL · Unilimdocument de 147 observations

Elevated severity in inhabitants over 15 years was observed during the malaria outbreak in the Kidal region.

MalipaludismeHAL · Unilimdocument de 80 observations

Recessive homozygotes for CD36 (rs321198) had significantly lower anti-malarial antibody levels to MSP2.

MaliMSP2 · paludismepublié 2015Malaria journaleurope_pmcdocument de 3 observations

0,412 per_1000_person_weeksMalaria incidence in the Kidal region was 0.412 cases per 1,000 person-weeks in 2021.

Malipaludismeobservé 2021HAL · Unilimdocument de 80 observations

17,4 %The malaria vaccine FMP2.1/AS02(A) had an efficacy of 17.4% against the primary end point of clinical malaria in Malian children.

Malipaludismepublié 2011The New England journal of medicineeurope_pmcdocument de 5 observationsDOI 10.1056/nejmoa1008115

6 foldAnti-AMA-1 antibodies increased significantly in both malaria vaccine groups, peaking at more than 6-fold higher than baseline in the full-dose group.

Malipaludismepublié 2008PloS oneeurope_pmcdocument de 2 observations

150 per_1000_person-yearsIn Mali, malaria incidence rose from 150 per 1000 person-years in 2021 to 172 per 1000 person-years in 2022.

Malipaludismeobservé 2021HAL · Unilimdocument de 111 observations

96,77 %Plasmodium falciparum était plus fréquent chez les individus symptomatiques (96,77 % vs. 93,24 %, p = 0,014).

MalipaludismeHAL · Unilimdocument de 214 observations

12,2 %Among children with sickle cell trait in Mali, the prevalence of severe versus uncomplicated malaria in children with the G6PD (A−) polymorphism was 12.2%.

MaliG6PD (A−) polymorphism · paludisme · trait drépanocytairepublié 2011American Journal of HematologyOpenAlexdocument de 9 observationsDOI 10.1002/ajh.22093

0,27 risk_ratioIn the study-level meta-analysis, treatment was associated with a reduction in Plasmodium falciparum prevalence with a risk ratio of 0.27.

Malipaludismepublié 2020The Lancet. Global healtheurope_pmcdocument de 6 observationsDOI 10.1016/s2214-109x(20)30325-9

13 msChez les patients porteurs de l'haplotype G/G du variant rs1805121, la médiane de la variation de l'intervalle QTc (ΔQTc) après traitement par DHA-PQ était de 13 ms (IC à 95 % : 4–23 ms).

MalipaludismeHAL · Unilimdocument de 62 observations

0,82 %Dans le groupe de dépistage passif, la prévalence des gamétocytes de Plasmodium falciparum était de 0,82 % chez les adolescents âgés de 10 à 14 ans.

MalipaludismeHAL · Unilimdocument de 214 observations

4 %In children who received RTS,S/AS01E vaccine in Burkina Faso and Mali, 4% showed a 10-fold increase in anti-CSP IgG antibody titres post-2020 as measured by Oxford MSD assay.

Burkina Faso · Malipaludismeobservé post-2020HAL · Unilimdocument de 105 observations

278 per_1000_person-yearsThere were 278 events of uncomplicated clinical malaria per 1000 person-years at risk in the vaccine-alone group.

Malipaludismepublié 2021The New England journal of medicineeurope_pmcdocument de 10 observations

79 %The 2018 DHS reported a utilization rate of LLINs of 79% in children under 1 year in Mali.

Malipaludismeobservé 2018HAL · Unilimdocument de 111 observations

85 %Au Mali, P. falciparum était responsable de 85 à 95 % des cas de paludisme rapportés selon la période de l’année.

MalipaludismeHAL · Unilimdocument de 214 observations

1 561 casesOver the whole period, 1,561 malaria cases were treated by mobile health teams.

MalipaludismeHAL · Unilimdocument de 80 observations

364 daysIn a cohort study in Bandiagara, Mali, from June 2009 to June 2010, hemoglobin AC and AS children had a median of 364 malaria-free days before first clinical malaria episode.

Malipaludismeobservé June 2009 to June 2010publié 2015The Journal of infectious diseaseseurope_pmcdocument de 10 observationsDOI 10.1093/infdis/jiv308

The malaria incidence was highest among children under five in Kidal, Mali during the 2024 epidemic.

MalipaludismeHAL · Unilimdocument de 80 observations

0,74 %Dans le groupe de dépistage actif, la prévalence des gamétocytes de Plasmodium falciparum était de 0,74 % chez les enfants âgés de 5 à 9 ans.

MalipaludismeHAL · Unilimdocument de 214 observations

1 480 décèsEn 2020, les formations sanitaires du Mali ont enregistré 1480 décès liés au paludisme.

Malipaludismeobservé 2020HAL · Unilimdocument de 214 observations

39 %In Mali, seasonal malaria chemoprevention reduced malaria illness incidence by 39% with an incidence rate ratio of 0.61 and 95% confidence interval 0.44–0.84.

MalipaludismeHAL · Unilimdocument de 110 observations

30 %Plasmodium vivax infections were detected in close to 30% of the cases among febrile patients recruited in five cities in Northern Mali.

Malipaludismepublié 2012Malaria journaleurope_pmc

0,26 proportionThe minor allele frequency of the E670G polymorphism in the study population sample was 0.26.

Malipaludismepublié 2018PloS oneeurope_pmcdocument de 6 observationsDOI 10.1371/journal.pone.0192850