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99,69 %SickleScan® had a negative predictive value of 99.69% to detect sickle cell disease compared to high-performance liquid chromatography.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

99,64 %The negative predictive value (NPV) of HemotypeSC® for detecting sickle cell disease was 99.64% (95% CI: 99.44–99.83).

MalidrépanocytoseHAL · Unilimdocument de 103 observations

99,67 %HemotypeSC® had a specificity of 99.67% (95% CI: 99.48–99.85) to detect sickle cell disease.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

1,64 %Among 3648 newborns diagnosed by HPLC in Mali from April 2021 to August 2021, 1.64% had sickle cell disease.

Malidrépanocytoseobservé April 2021 to August 2021HAL · Unilimdocument de 103 observations

95,8 %95.8% of mothers know sickle cell disease.

Malidrépanocytosepublié 2009Мир науки, культуры, образованияOpenAlexdocument de 12 observations

39,7 %The allelic frequency of the homozygote mutant variant of the CD209 gene promoter was 39.7% in African sickle cell disease patients and 48.7% in African healthy controls.

Malidrépanocytosepublié 2015PeerJOpenAlexdocument de 9 observationsDOI 10.7717/peerj.799

98,66 %HemotypeSC® had a negative predictive value of 98.66% to detect sickle cell disease carrier compared to high-performance liquid chromatography.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

98,6 %Both RDTs had a negative predictive value greater than 98.6% for excluding sickle cell disease compared with HPLC.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

5 casesDuring the study, 5 of 68 children with conditional TCD converted to abnormal TCD.

Malidrépanocytoseobservé 2008 to 2013publié 2013BloodOpenAlexdocument de 10 observations

99,4 %Of 3676 births, 3655 (99.4%) live-births were included and screened for sickle cell disease.

Malidrépanocytoseobservé 21 April to 17 August 2021HAL · Unilimdocument de 103 observations

99,75 %SickleScan® had a specificity of 99.75% [95% CI: 99.59–99.91] for diagnosing major sickle cell disease (SCD) compared to high-performance liquid chromatography in a study in Mali, April–August 2021.

Malidrépanocytoseobservé April–August 2021HAL · Unilimdocument de 103 observations

1,64 %The prevalence of sickle cell disease (SCD) among 3648 newborns in Mali was 1.64% (95% CI: 1.23–2.06).

Malidrépanocytoseobservé April–August 2021HAL · Unilimdocument de 103 observations

612 patients612 sickle cell disease patients and 149 healthy controls were included in the CADRE study in Cameroon, Mali, and Senegal.

Cameroun · Mali · SénégaldrépanocytoseHAL · Unilimdocument de 2 observations

99,67 %The specificity of HemotypeSC® for detecting sickle cell disease was 99.67% (95% CI: 99.48–99.85).

MalidrépanocytoseHAL · Unilimdocument de 103 observations

81,67 %The diagnostic performance of SickleScan® for sickle cell disease (SCD) in Mali from April to August 2021 showed a sensitivity of 81.67% [95% CI: 71.88–91.46].

Malidrépanocytoseobservé April–August 2021HAL · Unilimdocument de 103 observations

10,4 %The genotypic frequency of the homozygote mutant variant of the CD209 gene promoter was 10.4% in African sickle cell disease patients and 23.4% in African healthy controls.

Malidrépanocytosepublié 2015PeerJOpenAlexdocument de 9 observationsDOI 10.7717/peerj.799

0,63 %Among 3648 newborns diagnosed by HPLC in Mali from April 2021 to August 2021, 0.63% had HbSS.

Malidrépanocytoseobservé April 2021 to August 2021HAL · Unilimdocument de 103 observations

21,79 %Among 3648 newborns diagnosed by HPLC in Mali from April 2021 to August 2021, 21.79% were sickle cell disease carriers.

Malidrépanocytoseobservé April 2021 to August 2021HAL · Unilimdocument de 103 observations

2 %The prevalence of HbSS in Mali is around 2%.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

95,22 %HemotypeSC® had a sensitivity of 95.22% (95% CI: 93.74–96.70) to detect sickle cell disease carrier status.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

81,67 %SickleScan® had a sensitivity of 81.67% [95% CI: 71.88–91.46] for diagnosing major sickle cell disease (SCD) compared to high-performance liquid chromatography in a study in Mali, April–August 2021.

Malidrépanocytoseobservé April–August 2021HAL · Unilimdocument de 103 observations

12 g/dLHemoglobin levels < 12 g/dL were observed only in homozygous SCD patients.

Malidrépanocytosepublié 2024Hemoglobineurope_pmcdocument de 9 observations

5 000 nouveau-nésAu Mali, le criblage néonatal estime le nombre de naissances d’enfants drépanocytaires entre 5 000 et 6 000 par an.

MalidrépanocytoseHAL · Unilimdocument de 202 observations

99,7 %Among 3676 liveborn newborns from consenting mothers in Mali between April and August 2021, 3666 (99.7%) were screened at birth for sickle cell disease.

Malidrépanocytoseobservé April–August 2021HAL · Unilimdocument de 103 observations

5 timesDans la population sénégalaise, les patients avec «aucune complication vasculaire» sont cinq fois plus nombreux que dans la population malienne.

Mali · SénégaldrépanocytoseHAL · Unilimdocument de 202 observations