Explorer les evidences

93 %The SMC covered 93% of children aged 3–59 months.

MalipaludismeHAL · Unilimdocument de 95 observations

18,6 %The frequency of Pfmdr1 N86Y mutation in Plasmodium falciparum increased from 5.6% at baseline to 18.6% after 3 years of seasonal malaria chemoprevention (SMC) in Ouelessebougou, Mali.

Malipaludismeobservé 2014-2016publié 2022Malaria journaleurope_pmcdocument de 7 observationsDOI 10.1186/s12936-022-04059-z

70 %The efficacy of L9LS against Plasmodium falciparum infection, as compared with placebo, was 70% with the 300-mg dose.

Malipaludismepublié 2024The New England journal of medicineeurope_pmcdocument de 7 observations

1 498 deathsIn 2023, the National Malaria Control Program in Mali recorded 1,498 malaria deaths.

Malipaludismeobservé 2023HAL · Unilimdocument de 95 observations

49 %More children in the malaria vaccine group than in the control group had 3D7 GIA activity ≥15% 30 days after the last vaccination (day 90) (49% vs. 16%, p<0.0001).

Malipaludismepublié 2017PloS oneeurope_pmcdocument de 3 observations

1 000 per_1000_person_yearsMalaria incidence cases per 1,000 persons year were calculated for each health district.

MalipaludismeHAL · Unilimdocument de 95 observations

10 %Plasmodium malariae contributes up to 10% of malaria infections in sub-Saharan Africa.

Malipaludismepublié 2022Scientific reportseurope_pmcDOI 10.1038/s41598-022-26625-w

21,9 %Cross-reactivity against the SARS-CoV-2 S antigen was as high as 21.9% among populations not infected with SARS-CoV-2 living in malaria-endemic areas.

MaliCOVID-19 · paludismeHAL · Unilimdocument de 67 observations

181 daysIn a cohort study in Bandiagara, Mali, from June 2009 to June 2010, hemoglobin AA children had a median of 181 malaria-free days before first clinical malaria episode.

Malipaludismeobservé June 2009 to June 2010publié 2015The Journal of infectious diseaseseurope_pmcdocument de 10 observationsDOI 10.1093/infdis/jiv308

There was no difference in the prevalence of moderate or severe wasting between the groups in 2019.

Burkina Faso · Malipaludismeobservé 2019publié 2022Malaria journaleurope_pmcdocument de 7 observationsDOI 10.1186/s12936-022-04077-x

61 msLes porteurs de la variante génétique rs41314375 ont présenté une prolongation QTc de 61 ms après exposition à la pipéraquine, contre 14,4 ms chez les témoins.

MalipaludismeHAL · Unilimdocument de 62 observations

0,4 risk_ratioIn the study-level meta-analysis, treatment was associated with a reduction in clinical malaria with a risk ratio of 0.40.

Malipaludismepublié 2020The Lancet. Global healtheurope_pmcdocument de 6 observationsDOI 10.1016/s2214-109x(20)30325-9

66 %The efficacy of L9LS against Plasmodium falciparum infection, as compared with placebo, was 66% with the 150-mg dose.

Malipaludismepublié 2024The New England journal of medicineeurope_pmcdocument de 7 observations

113 per_1000_person-yearsThere were 113 events of uncomplicated clinical malaria per 1000 person-years at risk in the combination group.

Malipaludismepublié 2021The New England journal of medicineeurope_pmcdocument de 10 observations

5 foldAnti-AMA-1 antibodies increased significantly in both malaria vaccine groups, peaking at nearly 5-fold higher than baseline in the half-dose group.

Malipaludismepublié 2008PloS oneeurope_pmcdocument de 2 observations

0,02 %La prévalence des gamétocytes chez les enfants de moins d’un an était de 0,020 %.

MalipaludismeHAL · Unilimdocument de 214 observations

21 %Entre 2016 et 2019, le nombre de décès associés au paludisme au Mali a diminué de 21 %, passant de 0,76 à 0,59 décès pour 1000 habitants.

Malipaludismeobservé 2016 à 2019HAL · Unilimdocument de 214 observations

16 joursUne période pré-patente de 16 jours, considérée comme la plus courte, a été signalée pour une souche ouest-africaine de P. malariae.

MalipaludismeHAL · Unilimdocument de 214 observations

Le paludisme au Mali est saisonnier avec un pic d'incidence des cas cliniques et de mortalité entre septembre et novembre.

Malipaludismeobservé septembre–novembreHAL · Unilimdocument de 214 observations

7,32 %Dans le dépistage actif, la prévalence du paludisme était de 7,32 % chez les enfants âgés de 10 à 14 ans.

MalipaludismeHAL · Unilimdocument de 214 observations

15 odds_ratioThe odds ratio for greater susceptibility to severe malaria in heterozygous G6PD (A−) females with sickle cell trait was 15.

MaliG6PD (A−) deficiency · paludisme · trait drépanocytairepublié 2011American Journal of HematologyOpenAlexdocument de 9 observationsDOI 10.1002/ajh.22093

97,8 %A randomized, phase 3 study comparing artemether-lumefantrine (AL) Dispersible to crushed AL tablets in 899 African children reported a PCR-corrected cure rate of 97.8% at day 28 for AL Dispersible.

Malipaludismepublié 2015Antimicrobial agents and chemotherapyeurope_pmcdocument de 3 observations

229 000 000 casEn 2019, le nombre de cas de paludisme s'élevait à 229 millions de cas détectés.

Malipaludismeobservé 2019HAL · Unilimdocument de 214 observations

92,1 %In Mali, a retrospective study conducted at CHU Gabriel Touré in Bamako between 2014 and 2018 showed a reduction in cerebral malaria frequency from 92.1% to 83.5% after SMC introduction.

Malipaludismeobservé 2014–2018HAL · Unilimdocument de 147 observations

79,8 %The parasite positivity rate decreased from 79.8% on day 1 to 9.5% on day 2 for artemether-lumefantrine.

Malipaludismepublié 2018Malaria journaleurope_pmcdocument de 4 observations