Explorer les evidences

78,33 %The sensitivity of HemotypeSC® for detecting sickle cell disease was 78.33% (95% CI: 67.91–88.76).

MalidrépanocytoseHAL · Unilimdocument de 103 observations

145 individualsThe study included 145 sickle cell disease and 231 control individuals from Mali.

Malidrépanocytosepublié 2015PeerJOpenAlexdocument de 9 observationsDOI 10.7717/peerj.799

40 %Sickle cell disease carrier prevalence is 40% among some populations in central Africa (Congo, Zaire) and Nigeria.

Malidrépanocytosepublié 2009Мир науки, культуры, образованияOpenAlexdocument de 12 observations

7 %Zanthoxylum zanthoxyloides était utilisé contre la douleur liée à la drépanocytose avec une fréquence de citation de 7 %.

MalidrépanocytoseHAL · Unilimdocument de 20 observations

1,64 %The prevalence of sickle cell disease among 3648 newborns in Mali was 1.64% (95% CI: 1.23–2.06).

Malidrépanocytoseobservé April–August 2021HAL · Unilimdocument de 103 observations

36,7 %Linkage-to-care for sickle cell disease newborns was effective for 36.7% (22/60) within the first 6 months.

Malidrépanocytoseobservé first 6 monthsHAL · Unilimdocument de 103 observations

7 %Zanthoxylum zanthoxyloides était utilisé traditionnellement contre les douleurs liées à la drépanocytose avec une fréquence d'utilisation de 7 %.

MalidrépanocytoseHAL · Unilimdocument de 20 observations

2 407 patientsIn Mali, Cameroon, and Ivory Coast, 2407 sickle cell disease patients aged 3 years old and over were included in the study.

Cameroun · Côte d'Ivoire · Malidrépanocytosepublié 2017Bloodeurope_pmcdocument de 4 observationsDOI 10.1182/blood-2016-12-755777

0,37 g/dLConversion from conditional to abnormal TCD was associated with a mean decrease in hemoglobin value of 0.37 g/dL.

Malidrépanocytosepublié 2013BloodOpenAlexdocument de 10 observations

98,18 %HemotypeSC® had a specificity of 98.18% [95% CI: 97.69–98.67] for diagnosing possible sickle cell disease (SCD) compared to high-performance liquid chromatography in a study in Mali, April–August 2021.

Malidrépanocytoseobservé April–August 2021HAL · Unilimdocument de 103 observations

3 timesDans la population malienne, la proportion de patients présentant une microalbuminurie est trois fois plus élevée que dans la population sénégalaise.

Mali · SénégaldrépanocytoseHAL · Unilimdocument de 202 observations

4 casesDuring the study, 4 of 444 children with normal TCD converted to conditional TCD.

Malidrépanocytoseobservé 2008 to 2013publié 2013BloodOpenAlexdocument de 10 observations

99,64 %HemotypeSC® had a negative predictive value (NPV) of 99.64% (95% CI: 99.44–99.83) to detect sickle cell disease.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

100 %In Mali, rapid POC testing was 100% sensitive and specific among 160 cases and 80 controls.

Malidrépanocytosepublié 2018BMC hematologyeurope_pmcdocument de 7 observationsDOI 10.1186/s12878-018-0120-5

98,9 %SickleScan® had a negative predictive value of 98.90% to detect sickle cell disease carrier compared to high-performance liquid chromatography.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

1 per_100Au Mali, le Centre de Recherche et de Lutte contre la Drépanocytose a réduit le taux de mortalité des enfants drépanocytaires de moins de 5 ans sous suivi médical à moins de 1 %.

MalidrépanocytoseHAL · Unilimdocument de 857 observations

99,64 %HemotypeSC® had a negative predictive value of 99.64% to detect sickle cell disease compared to high-performance liquid chromatography.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

95 %Diagnostic performances to identify sickle cell disease carriers exceeded 95% for both rapid diagnostic tests.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

90 %Both RDTs had an area under the curve greater than 90% for identifying confirmed sickle cell disease.

MalidrépanocytoseHAL · Unilimdocument de 103 observations

99,4 %Among 3676 liveborn newborns from consenting mothers in Mali between April and August 2021, 3655 (99.4%) were enrolled in the newborn screening study.

Malidrépanocytoseobservé April–August 2021HAL · Unilimdocument de 103 observations

10 casesAmong 3655 newborns included in the diagnosis performance analysis in Mali in 2021, 10 were confirmed to have sickle cell disease by high-performance liquid chromatography (HPLC).

Malidrépanocytoseobservé 2021HAL · Unilimdocument de 103 observations

3,33 %Of 3636 SickleScan® test results, 121 (3.33%) were phenotype misclassifications compared to high-performance liquid chromatography (HPLC).

Malidrépanocytoseobservé 2021HAL · Unilimdocument de 103 observations

11 %11% of the homozygous Sickle Cell Disease patients experience stroke by age of 20 years.

Malidrépanocytosepublié 2013BloodOpenAlexdocument de 10 observations

2 409 patientsAmong 2409 sickle cell disease patients in the CADRE cohort from Ivory Coast, Cameroon, and Mali, 1751 had the SS-Sβ0 phenotype and 658 had the SC-Sβ+ phenotype.

Cameroun · Côte d'Ivoire · Malidrépanocytosepublié 2015BloodOpenAlexdocument de 16 observations

81,67 %SickleScan® had a sensitivity of 81.67% to detect sickle cell disease compared to high-performance liquid chromatography.

MalidrépanocytoseHAL · Unilimdocument de 103 observations