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14 000 newbornsApproximately 14,000 newborns in Kenya have Sickle Cell Disease annually.

Kenyadrépanocytosepublié 2026Annals of global healthPubMeddocument de 5 observations

1,4 %Among 143 children with sickle cell disease receiving hydroxyurea, 1.4% had high transcranial Doppler velocities (≥ 200 cm/s).

KenyadrépanocytosePubMeddocument de 4 observations

94 %Ninety-four percent of mothers accepted newborn screening for sickle cell disease.

Kenyadrépanocytosepublié 2025PloS onePubMeddocument de 2 observations

50 %During maximum tolerated dose (MTD) of hydroxyurea, transfusion incidence was reduced by 50% compared to fixed-dose hydroxyurea in African children with sickle cell anemia.

Kenyadrépanocytosepublié 2024American journal of hematologyPubMeddocument de 7 observations

21 %If widely implemented, universal testing and hydroxyurea treatment at maximum tolerated dose could potentially prevent 21% of all pediatric transfusions administered in sub-Saharan Africa.

Kenyadrépanocytosepublié 2024American journal of hematologyPubMeddocument de 7 observations

0,319 odds_ratioCarriage of HbSS was associated with reduced monocytosis in children with P. falciparum malaria in Kisumu County, Western Kenya.

Kenyadrépanocytose · paludismepublié 2020BMC infectious diseasesPubMeddocument de 8 observations

120 cm/sIn a cross-sectional study of 105 Kenyan children with sickle cell anaemia, mean cerebral blood flow velocity was 120 +/- 34.9 cm/s.

Kenyadrépanocytosepublié 2009British journal of haematologyeurope_pmcdocument de 4 observations

4,9 %Among 143 children with sickle cell disease receiving hydroxyurea, 4.9% had low transcranial Doppler velocities (< 50 cm/s).

KenyadrépanocytosePubMeddocument de 4 observations

515 000 infantsGlobally, approximately 515,000 infants with Sickle Cell Disease (SCD) are born every year.

Kenyadrépanocytosepublié 2026Annals of global healthPubMeddocument de 5 observations

12 %Four years later, 11 out of 95 Kenyan children with sickle cell anaemia had died, corresponding to a mortality rate of 12%.

Kenyadrépanocytoseobservé four years laterpublié 2009British journal of haematologyeurope_pmcdocument de 4 observations

87 %Minimum nocturnal SpO2 was lower in 54 Tanzanian children with sickle cell anaemia (87%, IQR 78.5-91%) compared to 95 Kenyan children with sickle cell anaemia (92%, IQR 86-95%) and 19 Tanzanian controls (90%, IQR 83.5-93%).

Kenya · Tanzaniedrépanocytosepublié 2016Archives of disease in childhoodeurope_pmcdocument de 3 observationsDOI 10.1136/archdischild-2014-306468

97 %Daytime SpO2 was lower in 65 Tanzanian children with sickle cell anaemia (median 97%, IQR 94-100%) than in 113 Kenyan children with sickle cell anaemia (median 99%, IQR 98-100%) and 20 Tanzanian controls (median 100%, IQR 98-100%).

Kenya · Tanzaniedrépanocytosepublié 2016Archives of disease in childhoodeurope_pmcdocument de 3 observationsDOI 10.1136/archdischild-2014-306468

80 %Approximately 80% of infants born with Sickle Cell Disease globally occur in Sub-Saharan Africa annually.

Kenyadrépanocytosepublié 2026Annals of global healthPubMeddocument de 5 observations

0,124 odds_ratioCarriage of HbSS was associated with reduced RBC count in children with P. falciparum malaria in Kisumu County, Western Kenya.

Kenyadrépanocytose · paludismepublié 2020BMC infectious diseasesPubMeddocument de 8 observations

3 %In better-resourced settings, 3% of children with Sickle Cell Disease die before the age of 5 years.

Kenyadrépanocytosepublié 2026Annals of global healthPubMeddocument de 5 observations

1,7 %Among severe maternal conditions in the study cohort from Migori, Kenya, sickle cell disease accounted for 1.7%.

Kenyadrépanocytosepublié 2023BMC pregnancy and childbirthPubMeddocument de 18 observations

3 casesIn a cross-sectional study of 105 Kenyan children with sickle cell anaemia, 3 had conditional cerebral blood flow velocity (170–199 cm/s).

Kenyadrépanocytosepublié 2009British journal of haematologyeurope_pmcdocument de 4 observations

0 casesIn a cross-sectional study of 105 Kenyan children with sickle cell anaemia, none had abnormal cerebral blood flow velocity (>200 cm/s).

Kenyadrépanocytosepublié 2009British journal of haematologyeurope_pmcdocument de 4 observations

0,318 odds_ratioCarriage of HbSS was associated with reduced haematocrit in children with P. falciparum malaria in Kisumu County, Western Kenya.

Kenyadrépanocytose · paludismepublié 2020BMC infectious diseasesPubMeddocument de 8 observations

10,8 per_100_person-yearsThe transfusion rate was 10.8 per 100 person-years on maximum tolerated dose (MTD) of hydroxyurea in African children with sickle cell anemia.

Kenyadrépanocytosepublié 2024American journal of hematologyPubMeddocument de 7 observations

50 %In Sub-Saharan Africa, 50%–80% of children with Sickle Cell Disease will die before the age of 5 years due to lack of comprehensive care.

Kenyadrépanocytosepublié 2026Annals of global healthPubMeddocument de 5 observations

0,325 odds_ratioCarriage of HbSS was associated with reduced MCHC in children with P. falciparum malaria in Kisumu County, Western Kenya.

Kenyadrépanocytose · paludismepublié 2020BMC infectious diseasesPubMeddocument de 8 observations

3,629 odds_ratioCarriage of HbAS was associated with increased micro-platelets in children with P. falciparum malaria in Kisumu County, Western Kenya.

Kenyadrépanocytose · paludismepublié 2020BMC infectious diseasesPubMeddocument de 8 observations

0,04 adjusted_odds_ratioMothers in formal employment were 25 times less likely to accept newborn screening for sickle cell disease than those who were students in the multivariate logistic analysis model (aOR = 0.04; 95% CI = 0.00–0.78; p = 0.034).

Kenyadrépanocytosepublié 2025PloS onePubMeddocument de 2 observations

97,9 %Mean nocturnal SpO2 was lower in 54 Tanzanian children with sickle cell anaemia (97.9%, IQR 95.4-99.3%) compared to 95 Kenyan children with sickle cell anaemia (99.0%, IQR 96.7-99.8%) and 19 Tanzanian controls (98.4%, IQR 97.5-99.1%).

Kenya · Tanzaniedrépanocytosepublié 2016Archives of disease in childhoodeurope_pmcdocument de 3 observationsDOI 10.1136/archdischild-2014-306468