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Although adult females had higher levels of antibodies to PfCSP, there was no evidence of improved protection compared to males.

Gabonpaludismepublié 2022Frontiers in immunologyPubMeddocument de 5 observations

Malaria is one of the leading causes of hospital visits and hospitalization in pediatric wards for children under 5 years old.

Gabonpaludismepublié 2021Malaria journalPubMeddocument de 9 observations

1 isolatesOne of the 16 apoptogenic Plasmodium falciparum isolates specifically targeted lung endothelial cells.

Gabonpaludismepublié 2017BMC Infectious DiseasesOpenAlexdocument de 12 observationsDOI 10.1186/s12879-017-2552-0

95 %Per-protocol analysis on day 28 showed a PCR corrected cure rate of 95% for artesunate-amodiaquine in children aged 6 months to 12 years in Lambaréné, Gabon.

Gabonpaludismepublié 2019Malaria journaleurope_pmcdocument de 4 observationsDOI 10.1186/s12936-019-3015-4

In the absence of helminth infection, a high anti-GMZ2 IgG concentration on D84 was significantly associated with protection against malaria.

Gabonpaludismepublié 2021PLoS neglected tropical diseaseseurope_pmcdocument de 4 observationsDOI 10.1371/journal.pntd.0009361

12,1 %The prevalence of triple mutations of Pfdhfr VIRNI was 12.1%.

Gabonpaludismeobservé 2016publié 2021Journal of global antimicrobial resistanceeurope_pmcdocument de 12 observations

46 %La prévalence de Plasmodium falciparum était de 46,0 % dans l'échantillon de 257 enfants.

GabonpaludismeHAL · Unilimdocument de 81 observations

113,8 nMEx vivo chloroquine susceptibility data revealed a stepwise decrease in the median chloroquine IC50 from 113.8 nM in 2004 to 2.1 nM in 2024 in Lambaréné, Gabon.

Gabonpaludismeobservé 2004publié 2026International journal of molecular scienceseurope_pmcdocument de 6 observations

74,29 %In 2019, the wild-type pfcrt haplotype CVMNK was observed in 74.29% of malaria-positive individuals in Libreville, Gabon.

Gabonpaludismeobservé 2019publié 2026Acta tropicaPubMeddocument de 13 observations

43 %Maternal malaria prevalence was 43% in the RECIPAL cohort from southern Benin.

Gabonpaludismepublié 2022PloS oneeurope_pmcdocument de 5 observations

4 genotypes_per_sampleThe number of genotypes per sample (MOI) was highest in P. malariae (n = 4).

Gabonpaludismepublié 2017Malaria journaleurope_pmcdocument de 6 observations

30 nMCompound 6i demonstrated potent activity against asexual blood-stage Plasmodium falciparum parasites with an IC50 of 30 nM against the Pf3D7 strain.

Gabonpaludismepublié 2024European journal of medicinal chemistryPubMeddocument de 5 observations

52,1 %La prévalence du parasite du paludisme à forme asexuée chez les enfants positifs pour Plasmodium spp. était de 52,1 % dans le groupe APOE Ɛ4 (89 sur 171).

GabonpaludismeHAL · Unilimdocument de 81 observations

19 %19% of Plasmodium ovale wallikeri infection-free intervals were estimated to end with reappearance by week 32.

Gabonpaludismepublié 2019Clinical infectious diseases : an official publication of the Infectious Diseases Society europe_pmcdocument de 5 observationsDOI 10.1093/cid/ciz131

50 patientsParasite elimination was achieved in all 50 patients within ≤72 hours, with a geometric mean time to elimination of 34 hours.

Gabonpaludismepublié 2003Antimicrobial agents and chemotherapyeurope_pmcdocument de 4 observationsDOI 10.1128/aac.47.3.901-904.2003

2,55 nmol/LThe 90% effective concentration (EC90) of artemisone against fresh Plasmodium falciparum isolates from Gabon is 2.55 nmol/L.

Gabonpaludismepublié 2006The American journal of tropical medicine and hygieneeurope_pmcdocument de 3 observationsDOI 10.4269/ajtmh.2006.75.637

250 000 000 infectionsPlasmodium falciparum is responsible for 200 to 300 million infections annually.

Gabonpaludismepublié 2009PLoS PathogensOpenAlexdocument de 3 observationsDOI 10.1371/journal.ppat.1000446

0,25 μMCompound 6i demonstrated low submicromolar activity against liver-stage Plasmodium berghei parasites with an IC50 of 0.25 μM.

Gabonpaludismepublié 2024European journal of medicinal chemistryPubMeddocument de 5 observations

21,4 %Parental administration of antimalarial drugs was found among 21.4% of the 2543 febrile children included in the studies conducted in 2008–2009 in Gabon.

Gabonpaludismeobservé 2008-2009publié 2011Sante (Montrouge, France)europe_pmcdocument de 6 observations

2,1 %Submicroscopic malaria infections were detected in 2.1% of people living with HIV residing in urban areas of Gabon.

Gabonpaludismeobservé 2015–2016publié 2018Transactions of the Royal Society of Tropical Medicine and Hygieneeurope_pmcdocument de 3 observations

247 000 000 casesMalaria sickened 247,000,000 people in 2021.

Gabonpaludismeobservé 2021publié 2023Expert review of vaccineseurope_pmcdocument de 5 observations

88,2 %Three-dose RTS,S/AS01 vaccine efficacy in the lowest-transmission-intensity group (0.25 cases per person-year) decreased from 88.2% to 15.0% over 4.5 years.

Gabonpaludismepublié 2022The Journal of infectious diseasesPubMeddocument de 5 observations

81,6 %Three-dose RTS,S/AS01 vaccine efficacy in the highest-transmission-intensity group (3 cases per person-year) decreased from 81.6% to -27.7% over 4.5 years.

Gabonpaludismepublié 2022The Journal of infectious diseasesPubMeddocument de 5 observations

8 casesAmong 253 patients with positive SARS-CoV-2 PCR and available thick blood smear in the LUH SiCOV from April to July 2020, 8 cases of malaria co-infection were identified.

GabonCOVID-19 · paludismeobservé April to July 2020publié 2022The Pan African medical journalPubMeddocument de 6 observations

0 patientsOf 72 patients with isolated hyperparasitaemia, none developed critical disease.

Gabonhyperparasitaemia · paludismeobservé 2013-2023publié 2025Journal of travel medicinePubMeddocument de 5 observations