Explorer les evidences

30 nMCompound 6i demonstrated potent activity against asexual blood-stage Plasmodium falciparum parasites with an IC50 of 30 nM against the Pf3D7 strain.

Gabonpaludismepublié 2024European journal of medicinal chemistryPubMeddocument de 5 observations

3 casesThree cases of breast cancer in men were observed at Military Teaching Hospital Omar Bongo Ondimba between January 2008 and December 2009.

Gaboncancer du seinobservé January 2008 to December 2009publié 2015Bulletin de la Societe de pathologie exotique (1990)PubMed

52,1 %La prévalence du parasite du paludisme à forme asexuée chez les enfants positifs pour Plasmodium spp. était de 52,1 % dans le groupe APOE Ɛ4 (89 sur 171).

GabonpaludismeHAL · Unilimdocument de 81 observations

68,6 %The majority of genital HPV-positive and genital HPV-negative women (68.6% and 68.7%, respectively) exhibited serum or cervicovaginal IgG to Gardasil-9® HR-HPV.

Gaboninfection à HPVpublié 2020PloS onePubMeddocument de 7 observations

19 %19% of Plasmodium ovale wallikeri infection-free intervals were estimated to end with reappearance by week 32.

Gabonpaludismepublié 2019Clinical infectious diseases : an official publication of the Infectious Diseases Society europe_pmcdocument de 5 observationsDOI 10.1093/cid/ciz131

50 patientsParasite elimination was achieved in all 50 patients within ≤72 hours, with a geometric mean time to elimination of 34 hours.

Gabonpaludismepublié 2003Antimicrobial agents and chemotherapyeurope_pmcdocument de 4 observationsDOI 10.1128/aac.47.3.901-904.2003

84 %The most frequently mentioned clinical symptoms attributed to loiasis were itching (84%), eye worm migration (59%), and conjunctivitis-like symptoms (53%).

GabonL. loa · loasepublié 2024PLoS neglected tropical diseaseseurope_pmcdocument de 7 observations

12 %In Lambaréné, Gabon, streptomycin resistance was observed in 12% of TB cases.

Gabontuberculosepublié 2016The American journal of tropical medicine and hygieneeurope_pmcdocument de 12 observationsDOI 10.4269/ajtmh.15-0668

70 %Parmi les 114 enfants drepanocytaires d’âge scolaire inclus dans l’étude, la scolarité était bonne ou excellente dans 70 % des cas.

Gabondrépanocytoseobservé décembre 2015 à décembre 2016publié 2018Health sciences and diseaseOpenAlexdocument de 6 observations

13 %Sickle cell disease is the third most common reason for hospital admission and represents 13% of total admissions in Gabon.

GabondrépanocytoseHAL · Unilimdocument de 71 observations

68,6 %More than two-third (68.6%) of the fifty-one immigrant women carried genital HPV.

Gabongenital HPVpublié 2020PloS onePubMeddocument de 7 observations

4 %The combined prevalence of HCV among blood donors in Gabon was 4.0%.

Gabonhépatite Cpublié 2024PloS onePubMeddocument de 5 observations

72 %72% of fathers had never been screened for sickle cell disease.

GabondrépanocytoseHAL · Unilimdocument de 90 observations

67,2 %The prevalence of HIV drug resistance was 67.2% among those who failed antiretroviral therapy in semi-rural Franceville, Gabon.

GabonVIH/sidapublié 2021The Journal of antimicrobial chemotherapyPubMeddocument de 7 observations

7 %Among Staphylococcus aureus isolates from skin and soft tissue infections with antimicrobial susceptibility testing, 7% (36/497) were identified as methicillin-resistant Staphylococcus aureus (MRSA).

Gabonskin and soft tissue infectionsobservé 2009–2019publié 2024Antimicrobial resistance and infection controleurope_pmcdocument de 5 observations

35 %Out of 344 Gabonese pregnant women, 120 (35%) were serologically positive for HHV-8.

GabonHHV-8publié 2015International journal of infectious diseases : IJID : official publication of the Internateurope_pmcdocument de 4 observationsDOI 10.1016/j.ijid.2015.08.004

4,6 %Human rhinovirus (HRV) was detected in 4.6% of the 156 respiratory virus-positive nasopharyngeal swab specimens collected in Gabon from March 2020 to July 2021.

Gabonhuman rhinovirusobservé March 2020 to July 2021publié 2024Viruseseurope_pmcdocument de 8 observations

21,2 %The population attributable fraction (PAF) of spleen volume ≤ 110 cm³ associated with Loa loa microfilaremia was 21.2%.

GabonloaseHAL · Unilimdocument de 153 observations

21,9 %Parmi les 1 489 échantillons pour lesquels l'espèce plasmodiale a pu être déterminée, 326 (21,9 %) présentaient une infection à Plasmodium malariae.

Gabonpaludisme à Plasmodium malariaeHAL · Unilimdocument de 36 observations

2,55 nmol/LThe 90% effective concentration (EC90) of artemisone against fresh Plasmodium falciparum isolates from Gabon is 2.55 nmol/L.

Gabonpaludismepublié 2006The American journal of tropical medicine and hygieneeurope_pmcdocument de 3 observationsDOI 10.4269/ajtmh.2006.75.637

59 casesFifty-nine of the 272 participants included in the study were positive for S. stercoralis infection at baseline.

GabonS. stercoralis infectionpublié 2025Parasitology researcheurope_pmcdocument de 7 observations

250 000 000 infectionsPlasmodium falciparum is responsible for 200 to 300 million infections annually.

Gabonpaludismepublié 2009PLoS PathogensOpenAlexdocument de 3 observationsDOI 10.1371/journal.ppat.1000446

0,25 μMCompound 6i demonstrated low submicromolar activity against liver-stage Plasmodium berghei parasites with an IC50 of 0.25 μM.

Gabonpaludismepublié 2024European journal of medicinal chemistryPubMeddocument de 5 observations

21,4 %Parental administration of antimalarial drugs was found among 21.4% of the 2543 febrile children included in the studies conducted in 2008–2009 in Gabon.

Gabonpaludismeobservé 2008-2009publié 2011Sante (Montrouge, France)europe_pmcdocument de 6 observations

25 %HPV-18 prevalence among HIV-infected women in Ouagadougou was 25.0%.

GabonVIH/sidaobservé 2009–2010publié 2011Acta tropicaeurope_pmcdocument de 8 observations