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13.8 %Among healthcare professionals in Sierra Leone surveyed from January to March 2022, 13.8% were classified as highly vaccine hesitant (above the 75th percentile of the VAX score).

Sierra LeoneCOVID-19observed January to March 2022published 2022Vaccineseurope_pmcdocument of 12 observations

4,000 casesIn advanced HIV disease in Sierra Leone, there are over 4000 annual cases of esophageal candidiasis.

Sierra Leoneesophageal candidiasis · VIH/sidapublished 2021Therapeutic advances in infectious diseaseeurope_pmcdocument of 9 observations

29.8 %The highest mortality among study participants with COVID-19 and sepsis or septic shock was 29.8%.

Sierra LeoneCOVID-19 · sepsis · septic shockpublished 2020Sepsis and septic shock in COVID-19: a scoping review of the research dataeurope_pmcdocument of 17 observationsDOI 10.21203/rs.3.rs-30474/v1

51.5 %The prevalence of advanced HIV was 51.5% among outpatients aged 15 to 24 years with HIV at a major hospital in Sierra Leone between September 2022 and March 2023.

Sierra LeoneVIH avancéobserved September 2022 to March 2023published 2023Prevalence and factors associated with advanced HIV disease among young people aged 15 - 2europe_pmcdocument of 8 observationsDOI 10.1101/2023.11.07.23296880

8.8 aORLiver fibrosis/cirrhosis was strongly associated with hepatitis B virus (HBV) infection among people living with HIV, with an adjusted odds ratio of 8.80.

Sierra Leonehépatite B · liver fibrosis/cirrhosispublished 2022Journal of clinical medicineeurope_pmcdocument of 9 observations

19,789 men_testedIn the pre-COVID-19 phase, 19,789 men were tested for HIV in Sierra Leone.

Sierra LeoneVIH/sidaobserved pre-COVID-19published 2025Impact of the COVID-19 pandemic on regional and national uptake of HIV testing services ineurope_pmcdocument of 11 observations

59.9 %59.9% of participants in the study were vaccine-hesitant, as determined by the VAX scale.

Sierra LeoneCOVID-19observed April to June 2022published 2023Vaccineseurope_pmcdocument of 5 observationsDOI 10.3390/vaccines11111685

9.89 aORLiver fibrosis/cirrhosis was associated with diabetes/prediabetes among people living with HIV, with an adjusted odds ratio of 9.89.

Sierra Leonediabetes/prediabetes · liver fibrosis/cirrhosispublished 2022Journal of clinical medicineeurope_pmcdocument of 9 observations

6.3 %HIV testing rate decreased by 6.3% during the COVID-19 period in Sierra Leone.

Sierra LeoneVIH/sidapublished 2025Impact of the COVID-19 pandemic on regional and national uptake of HIV testing services ineurope_pmcdocument of 11 observations

35.8 %Of 586 unique patients reviewed, 210 (35.8%) qualified as 'stable' for antiretroviral therapy delivery.

Sierra LeoneVIH/sidaobserved 2019-2020published 2021Global health actioneurope_pmcdocument of 4 observationsDOI 10.1080/16549716.2021.1947566

701 patientsOf 701 drug-resistant TB patients, 383 (54.6%) were registered pre-COVID-19, 228 (32.5%) during, and 92 (13.1%) post-COVID-19.

Sierra Leonedrug-resistant TBpublished 2026PLOS global public healtheurope_pmcdocument of 6 observations

26.9 %Among 197 patients with chronic respiratory symptoms in an urban tertiary hospital in Sierra Leone, 53 (26.9%) were on TB treatment at the time of recruitment.

Sierra Leonetuberculoseobserved November 2021 to July 2022published 2023PLoS neglected tropical diseaseseurope_pmcdocument of 9 observations

4.7 %Among 170 HIV patients screened at Connaught Hospital in Freetown, Sierra Leone, the prevalence of cryptococcal antigenaemia was 4.7%.

Sierra Leonecryptococcal antigenaemiaobserved 2018published 2020BMC infectious diseaseseurope_pmcdocument of 7 observationsDOI 10.1186/s12879-020-4862-x

533 casesThe study analysed Lassa fever susceptibility and fatal outcomes in 533 cases of Lassa fever and 1,986 population controls recruited over a 7 year period in Nigeria and Sierra Leone.

Nigeria · Sierra Leonefièvre de Lassaobserved 7 year periodpublished 2024Nature microbiologyeurope_pmcdocument of 2 observations

11.5 %The incidence of surgical site infection (SSI) among 338 adult patients undergoing surgery in Freetown, Sierra Leone between February and July 2021 was 11.5%.

Sierra Leonesurgical site infectionobserved February and July 2021published 2022Antimicrobial resistance and infection controleurope_pmcdocument of 15 observationsDOI 10.1186/s13756-022-01078-y

33 %Patients presenting with fewer than 100,000 EBOV copies per milliliter had a case fatality rate of 33%.

Sierra LeoneEBOVpublished 2014The New England journal of medicineeurope_pmcdocument of 14 observations

40 %Abdominal pain was present in 40% of patients with Ebola virus disease at presentation.

Sierra Leonemaladie à virus Ebolapublished 2014The New England journal of medicineeurope_pmcdocument of 14 observations

1.482 aORMalnourished patients had higher odds of treatment success for drug-resistant TB (adjusted odds ratio: 1.482).

Sierra Leonedrug-resistant TBpublished 2026PLOS global public healtheurope_pmcdocument of 6 observations

17.5 %Among 920 individuals screened for hepatitis B virus in Freetown, Sierra Leone, 161 had detectable HBsAg, corresponding to a seroprevalence of 17.5%.

Sierra Leonehépatite Bobserved October 1, 2019 through September 30, 2022published 2023Impact of COVID-19 on Hepatitis B Screening in Sierra Leone: Insights from a Community Phaeurope_pmcdocument of 8 observationsDOI 10.1101/2023.05.24.23290418

27 %In Sierra Leone in 2015, malaria was responsible for 27% of all deaths.

Sierra Leonepaludismeobserved 2015HAL · Unilimdocument of 80 observations

78.8 %Among 306 adult participants in Freetown, Sierra Leone, 78.8% stated they would be willing to attend clinic regularly.

Sierra Leonehépatite Bpublished 2022Assessment of Knowledge, Stigmatizing Attitudes and Health-Seeking Behaviors Regarding Hepeurope_pmcdocument of 3 observationsDOI 10.20944/preprints202211.0233.v1

52.9 %Of the 17 partners tested for HIV, 9 (52.9%) were positive.

Sierra LeoneVIH/sidaobserved 2017published 2019BMC research noteseurope_pmcdocument of 10 observations

Les restrictions appliquées contre les pays tels que le Libéria, la Sierra Leone, la Guinée et le Nigeria pendant l'épidémie d'Ebola couvraient en moyenne la période mensuelle allant d'août 2014 à mars 2016.

Liberia · Nigeria · Sierra Leonemaladie à virus Ebolaobserved août 2014 à mars 2016HAL · Unilimdocument of 82 observations

4,000 deathsLa Sierra Leone a enregistré environ 4 000 décès liés à l'Ebola.

Sierra Leonemaladie à virus EbolaHAL · Unilimdocument of 82 observations

52.8 %Among 197 patients with chronic respiratory symptoms in an urban tertiary hospital in Sierra Leone, 104 (52.8%) had been diagnosed with TB in the past.

Sierra Leonetuberculoseobserved November 2021 to July 2022published 2023PLoS neglected tropical diseaseseurope_pmcdocument of 9 observations