Gold tier: mechanically validated evidence, with its primary source.
682 evidence items · page 6 / 28
53.1 %53.1% of senior secondary school students in Surulere Local Government Area, Lagos, Nigeria knew sickle cell disease was an inherited condition.
Nigeriadrépanocytosepublished 2022African journal of primary health care & family medicinePubMeddocument of 11 observations
373 mFunctional status assessed by six-minute walk test was 373.00 ± 60.40 m in sickle cell patients versus 403.83 ± 72.87 m in controls (p=0.021).
Nigeriadrépanocytosepublished 2022West African journal of medicinePubMeddocument of 8 observations
1.1 %Among 3622 enrolled sickle cell disease patients in Nigeria, 1.1% had pulmonary hypertension.
Nigeriadrépanocytose · pulmonary hypertensionpublished 2020Blood cells, molecules & diseaseseurope_pmcdocument of 16 observations
The copper-to-zinc ratio was higher in sickle cell anaemia patients than in controls, with a p-value less than 0.001.
Nigeriadrépanocytosepublished 2019African health sciencesPubMeddocument of 6 observations
68.4 %The risk of prolonged QTc interval was 68.4% during vaso-occlusive crisis in children with sickle cell anemia.
Nigeriadrépanocytosepublished 2021HemoglobinPubMeddocument of 5 observations
13 %Approximately 13% of Sickle Cell Disease patients in Nigeria benefit from Hydroxyurea therapy.
Nigeriadrépanocytosepublished 2025PloS oneeurope_pmcdocument of 2 observations
62 percentThe median ejection fraction of SCA patients was 62.00 (IQR = 55.0–67.0), significantly less than that of controls, which was 68.00 (IQR = 65.8–73.0).
Nigeriadrépanocytosepublished 2026BMC cardiovascular disordersPubMeddocument of 6 observations
2.4 %Sickle Cell Disease was the third leading indirect cause of maternal mortality, accounting for 2.4% of cases.
Nigeriadrépanocytoseobserved 2007-2019published 2022BMC pregnancy and childbirthPubMeddocument of 10 observations
61 %At the 40% threshold, 61% of the poorest quartile of sickle cell disease patients experienced catastrophic expenditure.
Nigeriadrépanocytosepublished 2022PloS onePubMeddocument of 5 observations
44.9 %Ziziphus mauritiana at the high dose of 0.5 mg/ml caused a reduction in percentage of sickle red cells from 44.9% to 20.5% at 150 minutes.
Nigeriadrépanocytosepublished 2020West African journal of medicineeurope_pmcdocument of 3 observations
28.87 yearsThe mean age of the sickle cell patients was 28.87 ± 7.89 years.
Nigeriadrépanocytosepublished 2022West African journal of medicinePubMeddocument of 8 observations
71 %Chloroquine was found in the blood of 71% of homozygous alpha+-thalassaemic children.
Nigeriadrépanocytosepublished 2001Tropical medicine & international health : TM & IHeurope_pmcdocument of 8 observations
6.3 %Among 490 analysed alleles from 245 homozygous sickle cell disease patients in Nigeria, 31 (6.3%) had the Cameroon haplotype.
Nigeriadrépanocytosepublished 2021The Journal of international medical researchPubMeddocument of 5 observations
1 z_scoreNigerian SCA patients (n=154) had significant reductions in both FEV and FVC of ~1 z-score compared with local controls (n=364).
Nigeriadrépanocytosepublished 2019ThoraxPubMeddocument of 7 observations
7.6 %In a cross-sectional study of 405 Nigerian children, 7.6% were homozygous for alpha+-thalassaemia.
Nigeriadrépanocytosepublished 2001Tropical medicine & international health : TM & IHeurope_pmcdocument of 8 observations
69.1 %Hydroxyurea dose escalation beyond 20 mg/kg/day was required to attain significant reductions in the time-averaged mean of maximal velocities in 69.1% of the cases.
Nigeriadrépanocytosepublished 2021Pediatric blood & cancerPubMeddocument of 5 observations
150,000 infantsAn estimated 150,000 infants with sickle cell anemia are born annually in Nigeria.
Nigeriadrépanocytosepublished 2021Pediatric neurologyPubMeddocument of 4 observations
87.74 %In the study, 87.74% of children with sickle cell anaemia had mild disease severity.
Nigeriadrépanocytosepublished 2024West African journal of medicinePubMeddocument of 9 observations
5 patientsFive (8.6%) of the patients with acute leukaemia also had sickle cell disease.
Nigeriadrépanocytose · leukaemiapublished 2020African health sciencesPubMeddocument of 3 observations
40.1 %Pneumonia accounted for 40.1% of respiratory morbidities among sickle cell disease patients.
Nigeriadrépanocytose · pneumonieobserved 2012 to 2021published 2024PloS onePubMeddocument of 12 observations
1.52 ng/mlWomen with HbSS had significantly lower median AMH of 1.52 ng/ml compared to the HbAA group with median AMH of 3.80 ng/ml.
Nigeriadrépanocytosepublished 2026Scientific reportsPubMeddocument of 7 observations
46.2 %The most used medical coping mechanism for priapism among male patients with sickle cell disease in Ibadan, Nigeria, was cold shower, used by 46.2%.
Nigeriadrépanocytosepublished 2020West African journal of medicinePubMeddocument of 9 observations
97 %97.0% of senior secondary school students in Surulere Local Government Area, Lagos, Nigeria had a positive attitude towards sickle cell disease.
Nigeriadrépanocytosepublished 2022African journal of primary health care & family medicinePubMeddocument of 11 observations
19 casesGroup 1 (SCD) comprised 19 (27.1%) Hb SS and 16 (22.9%) Hb SC.
Nigeriadrépanocytosepublished 2025The Nigerian postgraduate medical journalPubMeddocument of 6 observations
3.19 cmMean left ventricular internal diameter in systole was 3.19 ± 0.57 cm in sickle cell patients versus 2.81 ± 0.45 cm in controls (p=0.000).
Nigeriadrépanocytosepublished 2022West African journal of medicinePubMeddocument of 8 observations
Every row leads to its source document. The figure shown counts the VALIDATED observations it carries, never the extracted ones: the two differ on most documents. The exact source excerpt is not published, due to copyright constraints.