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13.8 yearsThe mean age at onset of pubic hair development (Tanner stage PH2) was 13.8 years in girls with sickle cell anaemia.

Nigeriadrépanocytosepublished 2023West African journal of medicinePubMeddocument of 7 observations

Nitric oxide scavenging (NOS) and superoxide dismutase (SOD) activities as well as glutathione level were significantly lower in sickle cell anaemia individuals compared to controls.

Nigeriadrépanocytosepublished 2021African health sciencesPubMeddocument of 7 observations

20,000,000 peopleSickle cell anaemia affects 20-25 million people globally.

Nigeriadrépanocytosepublished 2026Scientific reportsPubMeddocument of 7 observations

There is a disproportionately high incidence of sickle-cell disease in Nigeria.

Nigeriadrépanocytosepublished 2016Pharmacology research & perspectiveseurope_pmcdocument of 5 observations

17 deathsAll 17 deaths occurred among patients with lower respiratory diseases.

Nigeriadrépanocytose · lower respiratory diseasesobserved 2012 to 2021published 2024PloS onePubMeddocument of 12 observations

6.6 %The caries experience of children with sickle-cell anaemia was 6.6% in the permanent dentition.

Nigeriacaries dentaires · drépanocytosepublished 2025BMC oral healthPubMeddocument of 8 observations

8 %Mean HbF level among HbSS participants was 8.0%.

Nigeriadrépanocytosepublished 2021West African journal of medicinePubMeddocument of 13 observations

96.2 %96.2% of study participants had good knowledge of what causes sickle cell disease.

Nigeriadrépanocytosepublished 2023Frontiers in geneticseurope_pmcdocument of 5 observationsDOI 10.3389/fgene.2023.1052444

359 patientsNorth East registered 359 patients with sickle cell disease, representing 4.6% of the total enrolled in Nigeria.

Nigeriadrépanocytosepublished 2022Frontiers in geneticseurope_pmcdocument of 8 observations

3 deathsA total of 3 deaths occurred in the moderate-dose hydroxyurea group.

Nigeriadrépanocytosepublished 2023BloodPubMeddocument of 8 observations

89.7 %Out of 378 participants, 339 (89.7%) were using hydroxyurea while 39 (10.3%) had stopped using hydroxyurea at the time of the study.

Nigeriadrépanocytosepublished 2022Frontiers in geneticseurope_pmcdocument of 10 observations

55 %Among 108 children who completed the feasibility trial for managing severe acute malnutrition in older children with sickle cell anemia in Nigeria, 55% (n = 59) had low food security and 34% (n = 37) had very low food security.

Nigeriadrépanocytose · malnutritionpublished 2025Pediatric blood & cancerPubMeddocument of 4 observations

88 %At the 10% threshold, 88% of the poorest quartile of sickle cell disease patients experienced catastrophic expenditure.

Nigeriadrépanocytosepublished 2022PloS onePubMeddocument of 5 observations

2.89 scoreThe mean Beck Hopelessness Scale (BHS) score was 2.89 among clinically stable Nigerian adults with sickle cell disease.

Nigeriadrépanocytosepublished 2020Nigerian journal of clinical practicePubMeddocument of 8 observations

23.7 mg/kg/dayThe minimum dose of hydroxyurea required to achieve significant decline in TCD velocities ranged from 15 to 31 mg/kg/day, with a mean of 23.7 mg/kg/day.

Nigeriadrépanocytosepublished 2021Pediatric blood & cancerPubMeddocument of 5 observations

23 patients23 had osteomyelitis.

Nigeriadrépanocytosepublished 2021Hematology (Amsterdam, Netherlands)PubMeddocument of 16 observations

130 childrenThe study included 130 children with sickle cell anaemia aged 2–16 years at National Hospital Abuja, Nigeria.

Nigeriadrépanocytosepublished 2021West African journal of medicinePubMeddocument of 5 observations

9 yearsThe mean age of the controls was 9.0 years with a standard deviation of 3.1 years.

Nigeriadrépanocytosepublished 2023Ghana medical journalPubMeddocument of 7 observations

0 %CAE had a specificity of 0% for identifying the AC genotype relative to PCR.

Nigeriadrépanocytosepublished 2021Global pediatric healtheurope_pmcdocument of 5 observations

12.2 %Only 96 (12.2%) of the 780 mothers were aware of comprehensive care for babies with sickle cell disease.

Nigeriadrépanocytosepublished 2023West African journal of medicinePubMeddocument of 5 observations

9.1 %Ten (9.1%) children with sickle cell disease had low serum iron status.

Nigeriadrépanocytosepublished 2023West African journal of medicinePubMeddocument of 8 observations

94 %Among 164 mothers of children with SCD in a southwestern state of Nigeria, 154 (94%) had encountered genetic counseling for SCD.

Nigeriadrépanocytosepublished 2020TheScientificWorldJournalPubMeddocument of 9 observations

70 %Lower respiratory disease was the most common respiratory entity among sickle cell disease patients, accounting for 70.0% of respiratory morbidities.

Nigeriadrépanocytose · lower respiratory diseaseobserved 2012 to 2021published 2024PloS onePubMeddocument of 12 observations

1 %The prevalence of sickle cell anaemia in Nigeria is 1-3%.

Nigeriadrépanocytosepublished 2026Scientific reportsPubMeddocument of 7 observations

3.98 odds_ratioIn multivariate analysis, hydroxyurea use was associated with painful crisis with an odds ratio of 3.98.

NigeriadrépanocytosePubMeddocument of 10 observations