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515,000 newbornsOver 515,000 newborns are diagnosed with sickle cell disease annually.

Nigeriadrépanocytosepublished 2025BMJ global healtheurope_pmcdocument of 4 observations

36.9 %The most common ECG abnormality seen in children with sickle cell anaemia attending Federal University Teaching Hospital Owerri is left ventricular hypertrophy, observed in 36.9% of the subjects.

Nigeriadrépanocytosepublished 2025BMC pediatricsPubMeddocument of 16 observations

Low level of nitric oxide scavenging (NOS) activity was associated with severe vaso-occlusive crisis in sickle cell anaemia individuals.

Nigeriadrépanocytose · vaso-occlusive crisispublished 2021African health sciencesPubMeddocument of 7 observations

60.9 %The prevalence of hypoxemia in males with SCA was 60.9%.

Nigeriadrépanocytose · hypoxaemiapublished 2024BMC research notesPubMeddocument of 3 observations

24.2 %The level of utilization of hydroxyurea in the treatment of sickle cell disease among care providers in Jos, Nigeria was 24.2%.

Nigeriadrépanocytosepublished 2021African health sciencesPubMeddocument of 5 observations

7.1 per_100_person-yearsThe incidence rates of recurrent strokes were 7.1 per 100 person-years in the low-dose hydroxyurea group.

Nigeriadrépanocytosepublished 2023BloodPubMeddocument of 8 observations

1.34 IU/mLThe mean VWF level in steady state was 1.34 ± 0.23 IU/mL.

Nigeriadrépanocytosepublished 2025Annals of African medicinePubMeddocument of 12 observations

6 %Neurological manifestations were present in half (n = 4) of all recorded deaths, with an overall mortality of 6% in the studied patients.

Nigeriadrépanocytoseobserved March 2022 and February 2025PubMeddocument of 8 observations

17.4 %In 17.4% of encounters, children with sickle cell disease managed by short-term emergency department observation care had their observation care terminated and converted to full admission.

Nigeriadrépanocytoseobserved July 2017 to June 2019published 2020Transactions of the Royal Society of Tropical Medicine and HygienePubMeddocument of 6 observations

The clinical manifestations of HbSS start between 3 and 5 months of life as a result of reduction in foetal hemoglobin.

Nigeriadrépanocytosepublished 2022Annals of medicinePubMeddocument of 6 observations

26 %Among 164 mothers of children with SCD in a southwestern state of Nigeria, 44 (26%) were undecided about prenatal SCD diagnosis.

Nigeriadrépanocytosepublished 2020TheScientificWorldJournalPubMeddocument of 9 observations

17.9 %The caries experience of children with sickle-cell anaemia was 17.9% in the primary dentition.

Nigeriacaries dentaires · drépanocytosepublished 2025BMC oral healthPubMeddocument of 8 observations

10.6 %10.6% of severe anaemia among children aged 6–59 months in Nigeria was attributable to sickle cell disease.

Nigeriaanémie · drépanocytoseobserved 2018published 2022BMJ openeurope_pmcdocument of 6 observationsDOI 10.1136/bmjopen-2022-063369

40 %Left ventricular hypertrophy was observed in 18 out of 45 (40.0%) pediatric sickle cell anaemia patients in crisis.

Nigeriadrépanocytoseobserved 2023published 2025BMC pediatricsPubMeddocument of 16 observations

385 USDAu Nigéria, la drépanocytose constitue un fardeau économique mensuel médian d'environ 385 USD par personne.

NigeriadrépanocytoseHAL · Unilimdocument of 857 observations

65.7 %Among 35 children with moderate sickle cell disease, 23 (65.7%) had ocular abnormalities.

Nigeriadrépanocytosepublished 2021European journal of ophthalmologyPubMeddocument of 3 observations

66.7 %A majority (66.7%) of the sickle cell disease patients had moderate grade anemia.

Nigeriadrépanocytoseobserved 2013 to 2014published 2022The Pan African medical journalPubMeddocument of 9 observations

59.1 %175 (59.1%) of the caregivers strongly agreed that Newborn Screening for Sickle Cell Disease helps in the early detection and management of Sickle Cell Disease.

Nigeriadrépanocytosepublished 2024Frontiers in public healtheurope_pmcdocument of 8 observations

98.55 %About 98.55% of the 138 newly diagnosed sickle cell disease patients had homozygous sickle-hemoglobin (SS) variant.

Nigeriadrépanocytoseobserved 2013 to 2014published 2022The Pan African medical journalPubMeddocument of 9 observations

89.9 %After a health education session, approximately 89.9% of pregnant women understood that the chance of conceiving a child with sickle cell disease was 25% for a couple with the sickle cell trait, compared to approximately 23.6% before the session.

Nigeriadrépanocytosepublished 2024BMC pregnancy and childbirthPubMeddocument of 6 observations

1.5 %Sickle cell anaemia affects 1-2% of the population in Sub-Saharan Africa.

Nigeriadrépanocytosepublished 2022Annals of medicinePubMeddocument of 6 observations

50 %Reports have shown that 50 to 80% of affected children in sub-Saharan African countries die annually.

Nigeriadrépanocytosepublished 2022Current stem cell research & therapyeurope_pmcdocument of 2 observations

1.3 %Among young Nigerian SCA patients, asymptomatic gallstones were found in 1.3% of those not in the low-activity UGT1A1 (TA)n genotypes subgroup.

Nigeriadrépanocytosepublished 2019BMC medical geneticsPubMeddocument of 6 observations

15 %The prevalence of A1298C was 15% (29 of 192).

Nigeriadrépanocytosepublished 2019The Pan African medical journalPubMeddocument of 2 observations

36.7 %36.7% of couples were completely unaware of sickle cell phenotypes.

Nigeriadrépanocytosepublished 2025BMC public healthPubMeddocument of 6 observations