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10 patients10 had stroke or other neurological impairment.

Nigeriadrépanocytosepublished 2021Hematology (Amsterdam, Netherlands)PubMeddocument of 16 observations

10.19 odds_ratioIn multivariate analysis, hyperesthesia was associated with painful crisis with an odds ratio of 10.19.

NigeriadrépanocytosePubMeddocument of 10 observations

In the prepubertal period, the haemoglobin SS (HbSS) participants had larger median ultrasound testicular volume (MUSTV) compared to the haemoglobin AA (HbAA) controls (p = 0.001).

Nigeriadrépanocytosepublished 2021Journal of tropical pediatricsPubMeddocument of 2 observations

1.6 %Among 17 newborns with sickle cell disease (HbSS and HbSC) identified in The Gambia, 2 (1.6%) were from the Jola ethnic group.

Nigeriadrépanocytosepublished 2024Hemoglobineurope_pmcdocument of 10 observations

376.3 ng/mlThe median red cell folate level in children with sickle cell anaemia during steady state was 376.30 ng/ml.

Nigeriadrépanocytosepublished 2022Malawi medical journal : the journal of Medical Association of MalawiPubMeddocument of 3 observations

24 %Meningitis and sickle cell anaemia each accounted for 6 (24%) of the 25 children with acute hemiplegia admitted to the University of Calabar Teaching Hospital.

Nigeriadrépanocytose · méningite (non précisée)published 2020The Pan African medical journalPubMeddocument of 8 observations

112.56 mmHgSickle cell patients had lower systolic blood pressure (112.56 ± 10.87 mmHg vs 115.42 ± 14.75 mmHg).

Nigeriadrépanocytosepublished 2022West African journal of medicinePubMeddocument of 8 observations

17.9 %Children with sickle cell anaemia had a dental caries experience of 17.9%, compared to 8.9% in children without sickle cell anaemia.

Nigeriadrépanocytosepublished 2025BMC research notesPubMeddocument of 5 observations

7 %The northwestern geopolitical zone of Nigeria had the highest pooled prevalence of sickle cell disease at 7.0%.

Nigeriadrépanocytosepublished 2025Systematic reviewsPubMeddocument of 7 observations

All the mean annular valves diameter, left ventricular internal dimension in systole and diastole, inter-sinus distance diameter and sinu-tubular junction diameter are higher in children with sickle cell anemia than controls.

Nigeriadrépanocytosepublished 2021Malawi medical journal : the journal of Medical Association of MalawiPubMeddocument of 3 observations

7.7 %The prevalence of HbSF was 7.7% among sickle cell disease patients.

Nigeriadrépanocytose · HbSFpublished 2022Mediterranean journal of hematology and infectious diseaseseurope_pmcdocument of 17 observationsDOI 10.4084/mjhid.2022.001

The mean pulse rate, diastolic, systolic, and mean arterial pressures were significantly higher in the cases than in the controls.

Nigeriadrépanocytosepublished 2023Ghana medical journalPubMeddocument of 7 observations

17 %Consultation requests for a presumptive diagnosis of sickle cell disease accounted for 17% of all haematology consultation requests at the University College Hospital, Ibadan between June 2015 and January 2016.

Nigeriadrépanocytoseobserved June 2015 to January 2016published 2020West African journal of medicinePubMeddocument of 7 observations

Significantly lower zinc levels were observed in sickle cell anaemia patients during vaso-occlusive crisis than in steady clinical state, with a p-value less than 0.001.

Nigeriadrépanocytosepublished 2019African health sciencesPubMeddocument of 6 observations

17.6 mg/dLThe mean serum creatinine among SCA patients was 17.6 ± 7.5 mg/dL.

Nigeriadrépanocytosepublished 2023Malawi medical journal : the journal of Medical Association of MalawiPubMeddocument of 12 observations

59.2 %Among the 130 children with sickle cell anaemia in the study, 59.2% were male.

Nigeriadrépanocytosepublished 2021West African journal of medicinePubMeddocument of 5 observations

0.8 z-scoreChildren with sickle cell anemia and an enrolled sibling had a mean BMI z-score change of 0.8.

Nigeriadrépanocytosepublished 2025Nutrition research (New York, N.Y.)PubMeddocument of 6 observations

4.9 %Psychosocial factors explained 4.9% of the variance in utility score in people with sickle cell disease.

Nigeriadrépanocytosepublished 2019PloS onePubMeddocument of 5 observations

0.27 gene_frequencyIn an area of intense malaria transmission in South-West Nigeria, the -alpha3.7 type of alpha+-thalassaemia was observed at a gene frequency of 0.27.

Nigeriadrépanocytosepublished 1999Tropical medicine & international health : TM & IHeurope_pmcdocument of 8 observations

48.8 %Among 205 patients with sickle cell disease, 99 (48.8%) had been transfused two or more times.

Nigeriadrépanocytosepublished 2025Transfusion and apheresis science : official journal of the World Apheresis Association : europe_pmcdocument of 9 observations

58.8 %An ischaemic ECG was observed in 20 (58.8%) SCA children during the steady state.

Nigeriadrépanocytosepublished 2020Paediatrics and international child healtheurope_pmcdocument of 8 observations

500 deaths_per_dayMore than 500 children with sickle cell anaemia die every day due to lack of access to early diagnosis and related treatment.

Nigeriadrépanocytosepublished 2024PloS oneeurope_pmcdocument of 3 observations

1 %Nigeria has an estimated prevalence of 1%–3% of its population affected by sickle cell disease.

Nigeriadrépanocytosepublished 2025Annals of African medicinePubMeddocument of 12 observations

74.3 %The majority of physicians (74.3%) prescribe hydroxyurea for sickle cell disease in Nigeria.

Nigeriadrépanocytosepublished 2021Frontiers in geneticseurope_pmcdocument of 3 observationsDOI 10.3389/fgene.2021.765958

70.79 mmHgSickle cell patients had lower diastolic blood pressure (70.79 ± 9.03 mmHg vs 71.27 ± 9.23 mmHg).

Nigeriadrépanocytosepublished 2022West African journal of medicinePubMeddocument of 8 observations