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108 childrenThe trial included 108 children with sickle cell anemia aged 5–12 years with severe malnutrition.

Nigeriadrépanocytose · malnutritionpublished 2025Nutrition research (New York, N.Y.)PubMeddocument of 6 observations

0.17 Cohen's_dWomen with sickle cell disease had lower utility scores with a small effect size (d = 0.17).

Nigeriadrépanocytosepublished 2019PloS onePubMeddocument of 5 observations

0.9 %CYP2C19 *2/*2 genotype frequency was 0.9% in the SCD group.

Nigeriadrépanocytosepublished 2010Journal of clinical pharmacy and therapeuticseurope_pmcdocument of 10 observations

16.7 %The overall hearing loss prevalence was 16.7% in sickle cell disease patients.

Nigeriadrépanocytosepublished 2025Nigerian journal of clinical practicePubMeddocument of 5 observations

75 %Most of the antibodies (75%) belonged to the Rh blood group system.

Nigeriadrépanocytosepublished 2021ImmunohematologyPubMeddocument of 7 observations

100 %For HbSS phenotype, isoelectric focusing showed 100% specificity, sensitivity, positive predictive value (PPV), and negative predictive value (NPV).

Nigeriadrépanocytosepublished 2022Frontiers in geneticseurope_pmcdocument of 23 observations

18.18 metabolic_ratioTwo non-SCD volunteers with metabolic ratios of 18.18 and 25.76 and one SCD patient with a metabolic ratio of 16.77 were classified as poor metabolizers of proguanil.

Nigeriadrépanocytosepublished 2016Pharmacology research & perspectiveseurope_pmcdocument of 5 observations

46.4 %The mutant genotypes MTR 2756 AG/GG were recorded in 46.4% of subjects with disease severity score >7.

Nigeriadrépanocytosepublished 2022West African journal of medicinePubMeddocument of 5 observations

0 %The overall prevalence of primary hypothyroidism among children with sickle cell anaemia in this study was 0%.

Nigeriadrépanocytose · primary hypothyroidismpublished 2023Ethiopian journal of health sciencesPubMeddocument of 7 observations

11.5 %Among 26 alloimmunized sickle cell disease participants, Lewis alloantibodies were observed in 11.5%.

Nigeriadrépanocytosepublished 2025Transfusion and apheresis science : official journal of the World Apheresis Association : europe_pmcdocument of 9 observations

Ventricular dysfunction was more prevalent in the crisis than in the steady state.

Nigeriadrépanocytosepublished 2020Cardiology in the youngPubMeddocument of 6 observations

9.8 %Headaches occurred in 9.8% of the 133 children with sickle cell disease.

Nigeriadrépanocytose · headacheobserved March 2022 and February 2025PubMeddocument of 8 observations

15.4 %15.4% of the participants had good knowledge of SCD.

Nigeriadrépanocytosepublished 2020The Pan African medical journalPubMeddocument of 8 observations

1.3 %1.3% of moderate-to-severe anaemia among children aged 6–59 months in Nigeria was attributable to sickle cell disease.

Nigeriaanémie · drépanocytoseobserved 2018published 2022BMJ openeurope_pmcdocument of 6 observationsDOI 10.1136/bmjopen-2022-063369

12.8 %Seizures were the most frequent neurological manifestation, occurring in 12.8% of the 133 children with sickle cell disease.

Nigeriadrépanocytose · seizuresobserved March 2022 and February 2025PubMeddocument of 8 observations

27.8 %Among 205 patients with sickle cell disease, 57 (27.8%) had never had a transfusion.

Nigeriadrépanocytosepublished 2025Transfusion and apheresis science : official journal of the World Apheresis Association : europe_pmcdocument of 9 observations

3 malesThree males and two females with sickle cell disease were described among the patients with acute leukaemia.

Nigeriadrépanocytose · leukaemiapublished 2020African health sciencesPubMeddocument of 3 observations

12 folliclesWomen with HbSS had significantly lower median AFC of 12.0 compared to the HbAA group with median AFC of 15.0.

Nigeriadrépanocytosepublished 2026Scientific reportsPubMeddocument of 7 observations

-0.616 correlation_coefficientGlomerular filtration rate was negatively correlated with irreversible percentage sickle cell count (r = -0.616, P = 0.0001).

Nigeriadrépanocytosepublished 2024The Nigerian postgraduate medical journalPubMeddocument of 10 observations

9.4 %The 17 death cases contributed 9.4% (95% CI 5.9 to 14.5) of all sickle cell disease admissions.

Nigeriadrépanocytoseobserved 2012 to 2021published 2024PloS onePubMeddocument of 12 observations

55.6 %Left ventricular hypertrophy was observed in 10 out of 45 (55.6%) pediatric sickle cell anaemia patients with vaso-occlusive crises.

Nigeriadrépanocytoseobserved 2023published 2025BMC pediatricsPubMeddocument of 16 observations

503 patientsThe study recruited 503 SCD patients aged ≥15 years from five Nigerian sites.

Nigeriadrépanocytosepublished 2025Gates open researchPubMeddocument of 5 observations

-0.366 correlation_coefficientHopelessness had a modest negative correlation with hemoglobin concentration (r = -0.366, P < 0.001) among clinically stable Nigerian adults with sickle cell disease.

Nigeriadrépanocytosepublished 2020Nigerian journal of clinical practicePubMeddocument of 8 observations

8.06 severity_scoreThe mean SCA severity score was 8.06 ± 3.64, signifying a moderate SCA severity in the study population.

Nigeriadrépanocytoseobserved between September 2018 and March 2019published 2021African health sciencesPubMeddocument of 3 observations

73.2 %30 (73.2%) of the healthcare workers have recommended Newborn Screening for Sickle Cell Disease to caregivers.

Nigeriadrépanocytosepublished 2024Frontiers in public healtheurope_pmcdocument of 8 observations