Gold tier: mechanically validated evidence, with its primary source.
682 evidence items · page 20 / 28
87.4 %The proportion of pregnant women with a high level of knowledge about sickle cell disease significantly increased from 12.6% in the pre-test to 87.4% in the post-test (p = 0.015).
Nigeriadrépanocytosepublished 2024BMC pregnancy and childbirthPubMeddocument of 6 observations
35.1 g/dLMean corpuscular hemoglobin concentration (MCHC) in steady state subjects was 35.1 ± 43.4.
Nigeriadrépanocytosepublished 2022The Pan African medical journalPubMeddocument of 14 observations
87.3 fLMean corpuscular volume (MCV) in crisis state subjects was 87.3 ± 8.2.
Nigeriadrépanocytosepublished 2022The Pan African medical journalPubMeddocument of 14 observations
6 per_100_person-yearsThe incidence rates of recurrent strokes were 6.0 per 100 person-years in the moderate-dose hydroxyurea group.
Nigeriadrépanocytosepublished 2023BloodPubMeddocument of 8 observations
0.229 correlation_coefficientThere was a significant positive correlation between SCA disease severity and serum urea (r = 0.229; p = 0.035).
Nigeriadrépanocytosepublished 2023Malawi medical journal : the journal of Medical Association of MalawiPubMeddocument of 12 observations
2 crises_per_yearFrequency of crisis ranged from 0 to >10/year median of 2.
Nigeriadrépanocytosepublished 2021Hematology (Amsterdam, Netherlands)PubMeddocument of 16 observations
150,000 newbornsApproximately 150,000 newborns are affected by sickle cell disease yearly in Nigeria.
NigeriadrépanocytosePubMeddocument of 7 observations
370 per_1000Children with sickle cell disease born between 2003 and 2013 in Nigeria had about 370 excess under-5 deaths per 1000 livebirths compared to children with HbAA.
Nigeriadrépanocytoseobserved 2003–2013published 2021The Lancet. Haematologyeurope_pmcdocument of 6 observations
Utility score in sickle cell disease was low, indicating a substantial impact of the disease on health-related quality of life.
Nigeriadrépanocytosepublished 2019PloS onePubMeddocument of 5 observations
2.5 %Sickle cell disease affects 2-3% of an estimated population of 160 million people in Nigeria.
Nigeriadrépanocytosepublished 2022West African journal of medicinePubMeddocument of 5 observations
86.3 %145 (86.3%) of the participants had improved PCV while using hydroxyurea.
Nigeriadrépanocytosepublished 2022Frontiers in geneticseurope_pmcdocument of 10 observations
8 subjectsGlobin analysis in 30 SCA subjects showed that eight had three alpha-globin genes.
Nigeriadrépanocytosepublished 1989African journal of medicine and medical scienceseurope_pmcdocument of 6 observations
101 participantsA total of 101 participants were randomly allocated to low-dose and moderate-dose hydroxyurea treatment groups.
Nigeriadrépanocytosepublished 2023BloodPubMeddocument of 8 observations
0.85 mmol/lThe mean serum magnesium of subjects in vaso-occlusive crisis was significantly higher compared to the steady state (0.85 ± 0.1 vs 0.83 ± 0.1 mmol/l, p = 0.032).
Nigeriadrépanocytosepublished 2025BMC pediatricsPubMeddocument of 3 observations
12 patients12 had cholelithiasis.
Nigeriadrépanocytosepublished 2021Hematology (Amsterdam, Netherlands)PubMeddocument of 16 observations
122 childrenFrom July 2017 to June 2019, 122 children with sickle cell disease were admitted to the emergency department for painful crises.
Nigeriadrépanocytoseobserved July 2017 to June 2019published 2020Transactions of the Royal Society of Tropical Medicine and HygienePubMeddocument of 6 observations
33.3 %33.3% of the patients with sickle cell disease in the study had impaired ability to concentrate their urine.
NigeriadrépanocytosePubMeddocument of 7 observations
15.6 yearsThe mean age at menarche was 15.6 years for menstruating sickle cell disease patients.
Nigeriadrépanocytosepublished 2021Annals of African medicinePubMeddocument of 4 observations
31 patients31 had nephropathy.
Nigeriadrépanocytosepublished 2021Hematology (Amsterdam, Netherlands)PubMeddocument of 16 observations
29 %Among 172 children with sickle cell disease, 29% (50/172) had never been transfused or had less than two transfusions per lifetime.
Nigeriadrépanocytosepublished 2022British journal of haematologyPubMeddocument of 7 observations
4,000,000 peopleSickle cell anaemia affects about 4 million people across the globe.
Nigeriadrépanocytosepublished 2021Hematology (Amsterdam, Netherlands)PubMeddocument of 16 observations
16 umol/LThe median direct bilirubin level was 16.0 umol/L with an interquartile range of 11.3–29.0 umol/L.
Nigeriadrépanocytosepublished 2023West African journal of medicinePubMeddocument of 7 observations
50 %For HbAC phenotype, isoelectric focusing showed a positive predictive value (PPV) of 50%.
Nigeriadrépanocytosepublished 2022Frontiers in geneticseurope_pmcdocument of 23 observations
19.27 %Le Nigeria a une prévalence de drépanocytose de 19,27 %.
NigeriadrépanocytoseHAL · Unilimdocument of 75 observations
21.55 kg/m²Sickle cell patients had lower Body Mass Index (21.55 ± 3.51 vs 24.94 ± 4.56 kg/m², p=0.000).
Nigeriadrépanocytosepublished 2022West African journal of medicinePubMeddocument of 8 observations
Every row leads to its source document. The figure shown counts the VALIDATED observations it carries, never the extracted ones: the two differ on most documents. The exact source excerpt is not published, due to copyright constraints.