Gold tier: mechanically validated evidence, with its primary source.
682 evidence items · page 18 / 28
20 subjectsGlobin analysis in 30 SCA subjects showed that 20 had four alpha-globin genes, eight had three, and two had two alpha-globin genes.
Nigeriadrépanocytosepublished 1989African journal of medicine and medical scienceseurope_pmcdocument of 6 observations
HbA2 was significantly elevated in HbSS individuals with two alpha gene deletions.
Nigeriaalpha thalassemia · drépanocytosepublished 2022Mediterranean journal of hematology and infectious diseaseseurope_pmcdocument of 17 observationsDOI 10.4084/mjhid.2022.001
95.6 %Among 135 physicians caring for SCD patients in a southwestern state of Nigeria, 129 (95.6%) routinely recommend premarital SCD genetic counseling and testing.
Nigeriadrépanocytosepublished 2020TheScientificWorldJournalPubMeddocument of 9 observations
86 %86% of respondents supported newborn screening for sickle cell disease.
Nigeriadrépanocytosepublished 2018Cureuseurope_pmcdocument of 3 observations
A simplified hydroxyurea dosing strategy achieved high levels of treatment adherence in paediatric sickle cell anaemia patients in South East Nigeria.
Nigeriadrépanocytoseobserved 2022–2024published 2025BMC pediatricsPubMeddocument of 3 observations
88.9 %Anaemia was prevalent in 88.9% of sickle cell anaemia individuals.
Nigeriadrépanocytosepublished 2021African health sciencesPubMeddocument of 7 observations
4.5 %Hepatitis C infection was observed in 4.5% of the children.
Nigeriadrépanocytose · hépatite Cpublished 2021West African journal of medicinePubMeddocument of 10 observations
90 %90.0% of senior secondary school students in Surulere Local Government Area, Lagos, Nigeria were aware of sickle cell disease.
Nigeriadrépanocytosepublished 2022African journal of primary health care & family medicinePubMeddocument of 11 observations
0.009 p-valueA significantly higher proportion of the cases than the controls had T wave abnormality (p = 0.009).
Nigeriadrépanocytosepublished 2023Ghana medical journalPubMeddocument of 7 observations
26 samplesAn additional 26 samples from a separate sickle cell disease cohort were genotyped.
Nigeriadrépanocytosepublished 2026African journal of laboratory medicineeurope_pmcdocument of 5 observations
Catalase activity was higher in sickle cell anaemia individuals compared to controls.
Nigeriadrépanocytosepublished 2021African health sciencesPubMeddocument of 7 observations
50 %The histological pattern in the 22 patients who had renal biopsies showed mesangioproliferative glomerulonephritis in 11 (50%) patients.
Nigeriadrépanocytose · mesangioproliferative glomerulonephritispublished 2024The Nigerian postgraduate medical journalPubMeddocument of 10 observations
20 %20% of respondents relied on faith when making marital decisions affecting sickle cell disease birth risk.
Nigeriadrépanocytosepublished 2025BMC public healthPubMeddocument of 6 observations
17.6 %The prevalence of alloimmunization in patients with sickle cell disease was 17.6%.
Nigeriadrépanocytosepublished 2025Transfusion and apheresis science : official journal of the World Apheresis Association : europe_pmcdocument of 9 observations
Significantly higher copper levels were observed in sickle cell anaemia patients during vaso-occlusive crisis than in steady clinical state, with a p-value less than 0.001.
Nigeriadrépanocytosepublished 2019African health sciencesPubMeddocument of 6 observations
2.5 %Among 3622 enrolled sickle cell disease patients in Nigeria, 2.5% had experienced stroke.
NigeriaAVC · drépanocytosepublished 2020Blood cells, molecules & diseaseseurope_pmcdocument of 16 observations
5.9 %The mean foetal haemoglobin (HbF) level in sickle cell anaemia patients in Nigeria was 5.9% with a standard deviation of 3.8%.
Nigeriadrépanocytosepublished 1990European journal of haematologyeurope_pmcdocument of 5 observations
97 %Two hundred and ninety (97%) of the caregivers expressed willingness to participate in the Newborn Screening for Sickle Cell Disease.
Nigeriadrépanocytosepublished 2024Frontiers in public healtheurope_pmcdocument of 8 observations
3.35 odds_ratioIn multivariate analysis, neuralgic pain was associated with painful crisis with an odds ratio of 3.35.
NigeriadrépanocytosePubMeddocument of 10 observations
180 ng/mlThe median serum ferritin level of children with sickle cell disease was 180.00 ng/ml with an interquartile range of 237.50 ng/ml.
Nigeriadrépanocytosepublished 2023West African journal of medicinePubMeddocument of 8 observations
0.351 correlation_coefficientHopelessness had a modest positive correlation with anxiety (r = 0.351, P < 0.001) among clinically stable Nigerian adults with sickle cell disease.
Nigeriadrépanocytosepublished 2020Nigerian journal of clinical practicePubMeddocument of 8 observations
2.5 %Nigeria has 2–3% of its population affected by sickle cell disease.
NigeriadrépanocytosePubMeddocument of 7 observations
42.3 %Left ventricular hypertrophy was observed in 42.3% of pediatric sickle cell anaemia patients with severe anaemia.
Nigeriadrépanocytoseobserved 2023published 2025BMC pediatricsPubMeddocument of 16 observations
6.3 %Among 3622 enrolled sickle cell disease patients in Nigeria, 6.3% had renal complications.
Nigeriadrépanocytose · renal complicationspublished 2020Blood cells, molecules & diseaseseurope_pmcdocument of 16 observations
31.8 %The incidence of bacterial infection in hospitalized children with sickle cell anaemia was 31.8%.
Nigeriadrépanocytosepublished 2021The Nigerian postgraduate medical journalPubMeddocument of 8 observations
Every row leads to its source document. The figure shown counts the VALIDATED observations it carries, never the extracted ones: the two differ on most documents. The exact source excerpt is not published, due to copyright constraints.