Gold tier: mechanically validated evidence, with its primary source.
682 evidence items · page 17 / 28
-0.336 correlation_coefficientGlomerular filtration rate was negatively correlated with fractional excretion of sodium (r = -0.336, P = 0.004).
Nigeriadrépanocytosepublished 2024The Nigerian postgraduate medical journalPubMeddocument of 10 observations
1 %Hydroxyurea utilization among Sickle Cell Disease patients in Sub-Saharan Africa stands at less than 1%.
Nigeriadrépanocytosepublished 2025PloS oneeurope_pmcdocument of 2 observations
53 %For HbAS phenotype, isoelectric focusing showed a positive predictive value (PPV) of 53%.
Nigeriadrépanocytosepublished 2022Frontiers in geneticseurope_pmcdocument of 23 observations
25.5 %The prevalence of pulmonary hypertension among children with sickle cell anaemia was 25.5%.
Nigeriadrépanocytose · pulmonary hypertensionpublished 2020BMC pediatricsPubMeddocument of 8 observations
Sickle cell anaemia participants had lower mean values of Total Cholesterol (TC), High Density Lipoprotein (HDL), and Low Density Lipoprotein (LDL) than controls, with p < 0.05.
Nigeriadrépanocytosepublished 2019The Pan African medical journalPubMeddocument of 4 observations
61 %Among 138 newly diagnosed sickle cell disease patients, 61% (1% SCD prevalence) were in the pediatric age-group.
Nigeriadrépanocytoseobserved 2013 to 2014published 2022The Pan African medical journalPubMeddocument of 9 observations
Alpha thalassaemia deletion significantly reduces the transfusion requirements of patients with sickle-cell anaemia.
Nigeriadrépanocytosepublished 1994European journal of haematologyeurope_pmcdocument of 2 observations
-3.7 z-scoreChildren with sickle cell anemia and severe malnutrition had a mean baseline BMI z-score of -3.7.
Nigeriadrépanocytose · malnutritionpublished 2025Nutrition research (New York, N.Y.)PubMeddocument of 6 observations
0.2 %Among 1,168 newborn babies screened in The Gambia from April 14 to August 12, 2023, two (0.2%) had heterozygous HbS and HbC (HbSC).
Nigeriadrépanocytoseobserved April 14 to August 12, 2023published 2024Hemoglobineurope_pmcdocument of 10 observations
38.9 %Left ventricular hypertrophy was observed in 7 out of 45 (38.9%) pediatric sickle cell anaemia patients with hyperhemolytic crises.
Nigeriadrépanocytoseobserved 2023published 2025BMC pediatricsPubMeddocument of 16 observations
Serum zinc level was lower in sickle cell anaemia patients than in controls, with a p-value less than 0.001.
Nigeriadrépanocytosepublished 2019African health sciencesPubMeddocument of 6 observations
A significantly different value (p < 0.05) was observed between number of transfusions per year and alpha globin gene status in 28 patients with sickle-cell anaemia.
Nigeriadrépanocytosepublished 1994European journal of haematologyeurope_pmcdocument of 2 observations
0.018 p-valueA significantly higher proportion of the cases than the controls had heart blocks (p = 0.018).
Nigeriadrépanocytosepublished 2023Ghana medical journalPubMeddocument of 7 observations
67.6 %For HbAA phenotype, isoelectric focusing showed a specificity of 67.6%.
Nigeriadrépanocytosepublished 2022Frontiers in geneticseurope_pmcdocument of 23 observations
3 %Cholecystitis was observed in 3.0% of the children.
Nigeriacholecystitis · drépanocytosepublished 2021West African journal of medicinePubMeddocument of 10 observations
The average serum magnesium was higher in the group with moderate to severe pain during vaso-occlusive crisis, but the difference was not statistically significant across the three pain severity groups (p = 0.315).
Nigeriadrépanocytosepublished 2025BMC pediatricsPubMeddocument of 3 observations
84.7 %For HbAA phenotype, isoelectric focusing showed a sensitivity of 84.7%.
Nigeriadrépanocytosepublished 2022Frontiers in geneticseurope_pmcdocument of 23 observations
2 femalesTwo females with sickle cell disease were described among the patients with acute leukaemia.
Nigeriadrépanocytose · leukaemiapublished 2020African health sciencesPubMeddocument of 3 observations
84.6 %318 (84.6%) of the participants had fewer hospital admissions while using hydroxyurea.
Nigeriadrépanocytosepublished 2022Frontiers in geneticseurope_pmcdocument of 10 observations
98.1 %The fractional excretion of sodium was elevated in 98.1% of patients with sickle cell disease.
Nigeriadrépanocytosepublished 2024The Nigerian postgraduate medical journalPubMeddocument of 10 observations
56.4 %Among male patients with sickle cell disease in Ibadan, Nigeria, who experienced priapism, fear of recurrence was reported by 56.4%.
Nigeriadrépanocytosepublished 2020West African journal of medicinePubMeddocument of 9 observations
23 patients23 had other complications.
Nigeriadrépanocytosepublished 2021Hematology (Amsterdam, Netherlands)PubMeddocument of 16 observations
71.6 %561 (71.6%) of the 780 mothers agreed that sickle cell disease can be ameliorated by newborn screening.
Nigeriadrépanocytosepublished 2023West African journal of medicinePubMeddocument of 5 observations
6.9 %The prevalence of HbSS α+2 was 6.9% among sickle cell disease patients.
Nigeriadrépanocytose · HbSS α+2published 2022Mediterranean journal of hematology and infectious diseaseseurope_pmcdocument of 17 observationsDOI 10.4084/mjhid.2022.001
607 U/LThe median serum lactate dehydrogenase level was 607.0 U/L with an interquartile range of 487.3–758.5 U/L.
Nigeriadrépanocytosepublished 2023West African journal of medicinePubMeddocument of 7 observations
Every row leads to its source document. The figure shown counts the VALIDATED observations it carries, never the extracted ones: the two differ on most documents. The exact source excerpt is not published, due to copyright constraints.