Gold tier: mechanically validated evidence, with its primary source.
682 evidence items · page 14 / 28
0.53 correlation_coefficientHopelessness had a modest positive correlation with depression (r = 0.530, P < 0.001) among clinically stable Nigerian adults with sickle cell disease.
Nigeriadrépanocytosepublished 2020Nigerian journal of clinical practicePubMeddocument of 8 observations
1 %The previously reported national prevalence range of sickle cell disease (SCD) in Nigeria was 1% to 3%.
Nigeriadrépanocytosepublished 2025West African journal of medicinePubMeddocument of 8 observations
55 %Seventeen out of 31 tertiary hospitals (55%) offered chronic transfusion therapy (CTT) by top-up or manual exchange transfusion.
Nigeriadrépanocytoseobserved 2014published 2016International healtheurope_pmcdocument of 11 observations
100 %For HbAC phenotype, isoelectric focusing showed a negative predictive value (NPV) of 100%.
Nigeriadrépanocytosepublished 2022Frontiers in geneticseurope_pmcdocument of 23 observations
33.3 %Among survivors, approximately one-third had residual neurological deficits.
Nigeriadrépanocytoseobserved March 2022 and February 2025PubMeddocument of 8 observations
Stroke history was less frequent in the Ibadan patients aged ≥18 years.
NigeriaAVC · drépanocytosepublished 2014Hemoglobineurope_pmcdocument of 5 observations
75 %About 75% of annual affected babies with sickle cell disease worldwide are born in sub-Saharan African countries.
Nigeriadrépanocytosepublished 2018Cureuseurope_pmcdocument of 3 observations
66 %The most reported complication of sickle cell disease requiring hospital management is pain crises, ranging from 66% to 96%.
Nigeriadrépanocytose · pain crisespublished 2025Communications medicineeurope_pmcdocument of 4 observations
16.8 x10⁹/LWhite blood cell count in crisis state subjects was 16.8 ± 3.4.
Nigeriadrépanocytosepublished 2022The Pan African medical journalPubMeddocument of 14 observations
12.09 cmSickle cell anemia subjects had a larger mean hepatic size than non-SCA subjects (12.09 cm ± 2.23 vs. 11.67 cm ± 1.96).
Nigeriadrépanocytosepublished 2023Nigerian journal of clinical practicePubMeddocument of 9 observations
48 %48% of the interviewed students had bad control practices regarding sickle cell disease.
Nigeriadrépanocytosepublished 2021The Pan African medical journalPubMeddocument of 7 observations
38.4 %The prevalence of myocardial ischemia measuring both cardiac troponin T and electrocardiography in children with sickle cell anemia during vaso-occlusive crisis was 38.4%.
Nigeriadrépanocytose · myocardial ischemiaobserved 2019published 2024Journal of tropical pediatricsPubMeddocument of 6 observations
3,190 childrenOver a 6-month enrollment period, 3190 children aged from 5 to 12 years with sickle cell anemia were evaluated for eligibility.
Nigeriadrépanocytosepublished 2023Blood advancesPubMeddocument of 6 observations
9 %Paralysis occurred in 9.0% of the 133 children with sickle cell disease.
Nigeriadrépanocytose · paralysisobserved March 2022 and February 2025PubMeddocument of 8 observations
75 %75% of annual global births with sickle cell disease occur in Africa.
Nigeriadrépanocytosepublished 2024BMJ openeurope_pmcdocument of 2 observations
400,000 births_per_yearRoughly 400,000 babies are born with sickle cell disease each year worldwide.
Nigeriadrépanocytosepublished 2024PloS oneeurope_pmcdocument of 3 observations
0.6 %0.6% of mild-to-severe anaemia among children aged 6–59 months in Nigeria was attributable to sickle cell disease.
Nigeriaanémie · drépanocytoseobserved 2018published 2022BMJ openeurope_pmcdocument of 6 observationsDOI 10.1136/bmjopen-2022-063369
10.6 %10.6% of the SCA patients had severe disease.
Nigeriadrépanocytosepublished 2023Malawi medical journal : the journal of Medical Association of MalawiPubMeddocument of 12 observations
5 patients5 had pulmonary hypertension.
Nigeriadrépanocytosepublished 2021Hematology (Amsterdam, Netherlands)PubMeddocument of 16 observations
2.733 mmol/lThe SCA group had significantly lowered calcium levels (2.733 ± 1.593 mmol/l) compared to the HBAA control group (1.846 ± 1.123 mmol/l) with p=0.009.
Nigeriadrépanocytoseobserved 2020-12-02 to 2021-03-31published 2022The Pan African medical journalPubMeddocument of 4 observations
92.5 %347 (92.5%) of the participants had fewer pain crises while using hydroxyurea.
Nigeriadrépanocytosepublished 2022Frontiers in geneticseurope_pmcdocument of 10 observations
25 %Among 164 mothers of children with SCD in a southwestern state of Nigeria, 42 (25%) were aware of prenatal SCD diagnosis.
Nigeriadrépanocytosepublished 2020TheScientificWorldJournalPubMeddocument of 9 observations
1.6 %1.6 percent of 181 Nigerian subjects had the beta S gene linked to the Hpa-I 7.6 kb fragment.
Nigeriadrépanocytosepublished 1989Tropical and geographical medicineeurope_pmcdocument of 4 observations
Right atrial area was the only significant determinant of relative systemic hypertension in patients with sickle cell anaemia.
Nigeriadrépanocytose · relative systemic hypertensionpublished 2020Indian heart journalPubMeddocument of 3 observations
84.3 %CYP2C19 *1 allele frequency was 84.3% in Nigerian patients with sickle-cell disease.
Nigeriadrépanocytose · paludismepublished 2010Journal of clinical pharmacy and therapeuticseurope_pmcdocument of 10 observations
Every row leads to its source document. The figure shown counts the VALIDATED observations it carries, never the extracted ones: the two differ on most documents. The exact source excerpt is not published, due to copyright constraints.