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476 womenOf 619 screened pregnant women with HbSS and HbSC, 476 eligible women were recruited into a randomized controlled trial in southwest Nigeria.

Nigeriadrépanocytoseobserved July 1, 2020 to May 27, 2024published 2026The Lancet. Global healthPubMeddocument of 13 observations

0 %CAE had a sensitivity of 0% for identifying the AC genotype relative to PCR.

Nigeriadrépanocytosepublished 2021Global pediatric healtheurope_pmcdocument of 5 observations

13,403 patientsThe SickleInAfrica consortium registry enrolled 13,403 sickle cell disease patients from 2017 to 2021 across 31 facilities in Ghana, Nigeria, and Tanzania.

Ghana · Nigeria · Tanzaniedrépanocytoseobserved 2017-2021published 2025EJHaemeurope_pmcdocument of 7 observations

1 %The prevalence of sickle cell disease among the pediatric age-group was 1%.

Nigeriadrépanocytoseobserved 2013 to 2014published 2022The Pan African medical journalPubMeddocument of 9 observations

5.6 %Left ventricular hypertrophy was observed in 1 out of 45 (5.6%) pediatric sickle cell anaemia patients with sequestration crises.

Nigeriadrépanocytoseobserved 2023published 2025BMC pediatricsPubMeddocument of 16 observations

88.89 %88.89% of sickle cell anaemia patients screened using Natriuretic peptide were at risk of developing pulmonary hypertension (NT-proBNP levels ≥ 160 pg/ml).

Nigeriadrépanocytosepublished 2022West African journal of medicinePubMeddocument of 8 observations

25.6 %Only 25.6% of study participants knew about the positive role of community engagement and education in reducing the prevalence of sickle cell disease and alleviating sickle cell disease crises.

Nigeriadrépanocytosepublished 2023Frontiers in geneticseurope_pmcdocument of 5 observationsDOI 10.3389/fgene.2023.1052444

100 %The sensitivity and specificity for SS, SC, AS, AC, and AA genotypes by HemotypeSC relative to PCR were each 100%.

Nigeriadrépanocytosepublished 2021Global pediatric healtheurope_pmcdocument of 5 observations

5.9 %Asymptomatic gallstones were found in 5.9% of young Nigerian SCA patients.

Nigeriadrépanocytosepublished 2019BMC medical geneticsPubMeddocument of 6 observations

7 %Sickle cell disease contributes up to 7% to 16% of under-five mortality in African countries.

Nigeriadrépanocytosepublished 2025Communications medicineeurope_pmcdocument of 4 observations

7,256 casesOf the 72,333 paediatric admissions, 7,256 (10.0%) had sickle cell disease.

Nigeriadrépanocytoseobserved 2012 to 2021published 2024PloS onePubMeddocument of 12 observations

97 %The common haplotype (- - - - + + - +) was present in 97% of the beta s chromosomes examined in sickle cell anaemia patients in Nigeria.

Nigeriadrépanocytosepublished 1990European journal of haematologyeurope_pmcdocument of 5 observations

150,000 cases_per_yearIn Nigeria, about 150000 babies are born annually with sickle cell disease (SCD).

Nigeriadrépanocytosepublished 2020PloS onePubMeddocument of 4 observations

-0.274 correlation_coefficientZinc correlated inversely with disease severity scores in sickle cell anaemia patients, with a Spearman correlation coefficient of -0.2743 and a p-value of 0.006.

Nigeriadrépanocytosepublished 2019African health sciencesPubMeddocument of 6 observations

HSP 70 levels were significantly increased (P<0.005) in sickle cell disease subjects with HbSS and HbSC genotypes in both steady state and crisis compared to controls with HbAA and HbAS genotypes.

Nigeriadrépanocytosepublished 2022The Pan African medical journalPubMeddocument of 14 observations

94 %94% of sickle cell anaemia patients in Nigeria had foetal haemoglobin (HbF) levels below 10%.

Nigeriadrépanocytosepublished 1990European journal of haematologyeurope_pmcdocument of 5 observations

63 %63.0% of senior secondary school students in Surulere Local Government Area, Lagos, Nigeria had good knowledge of sickle cell disease.

Nigeriadrépanocytosepublished 2022African journal of primary health care & family medicinePubMeddocument of 11 observations

52.9 %Among 3622 enrolled sickle cell disease patients in Nigeria, 1889 (52.9%) were females.

Nigeriadrépanocytosepublished 2020Blood cells, molecules & diseaseseurope_pmcdocument of 16 observations

386.4 cells/μLAbsolute neutrophil count in steady state subjects was 386.4 ± 31.

Nigeriadrépanocytosepublished 2022The Pan African medical journalPubMeddocument of 14 observations

-0.07 BMI_z-score_per_unit_food_security_scoreHigher scores on the continuous food security measure, indicating lower food security, were associated with lower BMI z-scores after malnutrition treatment (β = -0.07, p = 0.016).

Nigeriadrépanocytose · malnutritionpublished 2025Pediatric blood & cancerPubMeddocument of 4 observations

26 %Isoelectric focusing (IEF) tests identified 133 (26.0%) HbAS phenotypes among 511 newborns.

Nigeriadrépanocytosepublished 2022Frontiers in geneticseurope_pmcdocument of 23 observations

13.6 %The prevalence of cholelithiasis in pediatric sickle cell disease in Lagos was 13.6%.

Nigeriacholelithiasis · drépanocytosepublished 2022Annals of African medicinePubMeddocument of 6 observations

0.49 z_scoreAt the end of the trial, the mean change in body mass index z score was 0.49.

Nigeriadrépanocytosepublished 2023Blood advancesPubMeddocument of 6 observations

8.7 %The prevalence of overt stroke among SCD patients in Nigeria was 8.7%.

NigeriaAVC · drépanocytosepublished 2015Cardiovascular journal of Africaeurope_pmcdocument of 2 observationsDOI 10.5830/cvja-2015-040

0.001 p-valueOverweight/obesity in sickle cell anemia was significantly associated with upper social class (P = 0.001).

Nigeriadrépanocytose · overweight/obesitypublished 2020Nigerian journal of clinical practicePubMeddocument of 9 observations