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78.33 %The sensitivity of HemotypeSC® for detecting sickle cell disease was 78.33% (95% CI: 67.91–88.76).

MalidrépanocytoseHAL · Unilimdocument of 103 observations

145 individualsThe study included 145 sickle cell disease and 231 control individuals from Mali.

Malidrépanocytosepublished 2015PeerJOpenAlexdocument of 9 observationsDOI 10.7717/peerj.799

40 %Sickle cell disease carrier prevalence is 40% among some populations in central Africa (Congo, Zaire) and Nigeria.

Malidrépanocytosepublished 2009Мир науки, культуры, образованияOpenAlexdocument of 12 observations

7 %Zanthoxylum zanthoxyloides était utilisé contre la douleur liée à la drépanocytose avec une fréquence de citation de 7 %.

MalidrépanocytoseHAL · Unilimdocument of 20 observations

1.64 %The prevalence of sickle cell disease among 3648 newborns in Mali was 1.64% (95% CI: 1.23–2.06).

Malidrépanocytoseobserved April–August 2021HAL · Unilimdocument of 103 observations

36.7 %Linkage-to-care for sickle cell disease newborns was effective for 36.7% (22/60) within the first 6 months.

Malidrépanocytoseobserved first 6 monthsHAL · Unilimdocument of 103 observations

7 %Zanthoxylum zanthoxyloides était utilisé traditionnellement contre les douleurs liées à la drépanocytose avec une fréquence d'utilisation de 7 %.

MalidrépanocytoseHAL · Unilimdocument of 20 observations

2,407 patientsIn Mali, Cameroon, and Ivory Coast, 2407 sickle cell disease patients aged 3 years old and over were included in the study.

Cameroun · Côte d'Ivoire · Malidrépanocytosepublished 2017Bloodeurope_pmcdocument of 4 observationsDOI 10.1182/blood-2016-12-755777

0.37 g/dLConversion from conditional to abnormal TCD was associated with a mean decrease in hemoglobin value of 0.37 g/dL.

Malidrépanocytosepublished 2013BloodOpenAlexdocument of 10 observations

98.18 %HemotypeSC® had a specificity of 98.18% [95% CI: 97.69–98.67] for diagnosing possible sickle cell disease (SCD) compared to high-performance liquid chromatography in a study in Mali, April–August 2021.

Malidrépanocytoseobserved April–August 2021HAL · Unilimdocument of 103 observations

3 timesDans la population malienne, la proportion de patients présentant une microalbuminurie est trois fois plus élevée que dans la population sénégalaise.

Mali · SénégaldrépanocytoseHAL · Unilimdocument of 202 observations

4 casesDuring the study, 4 of 444 children with normal TCD converted to conditional TCD.

Malidrépanocytoseobserved 2008 to 2013published 2013BloodOpenAlexdocument of 10 observations

99.64 %HemotypeSC® had a negative predictive value (NPV) of 99.64% (95% CI: 99.44–99.83) to detect sickle cell disease.

MalidrépanocytoseHAL · Unilimdocument of 103 observations

100 %In Mali, rapid POC testing was 100% sensitive and specific among 160 cases and 80 controls.

Malidrépanocytosepublished 2018BMC hematologyeurope_pmcdocument of 7 observationsDOI 10.1186/s12878-018-0120-5

98.9 %SickleScan® had a negative predictive value of 98.90% to detect sickle cell disease carrier compared to high-performance liquid chromatography.

MalidrépanocytoseHAL · Unilimdocument of 103 observations

1 per_100Au Mali, le Centre de Recherche et de Lutte contre la Drépanocytose a réduit le taux de mortalité des enfants drépanocytaires de moins de 5 ans sous suivi médical à moins de 1 %.

MalidrépanocytoseHAL · Unilimdocument of 857 observations

99.64 %HemotypeSC® had a negative predictive value of 99.64% to detect sickle cell disease compared to high-performance liquid chromatography.

MalidrépanocytoseHAL · Unilimdocument of 103 observations

95 %Diagnostic performances to identify sickle cell disease carriers exceeded 95% for both rapid diagnostic tests.

MalidrépanocytoseHAL · Unilimdocument of 103 observations

90 %Both RDTs had an area under the curve greater than 90% for identifying confirmed sickle cell disease.

MalidrépanocytoseHAL · Unilimdocument of 103 observations

99.4 %Among 3676 liveborn newborns from consenting mothers in Mali between April and August 2021, 3655 (99.4%) were enrolled in the newborn screening study.

Malidrépanocytoseobserved April–August 2021HAL · Unilimdocument of 103 observations

10 casesAmong 3655 newborns included in the diagnosis performance analysis in Mali in 2021, 10 were confirmed to have sickle cell disease by high-performance liquid chromatography (HPLC).

Malidrépanocytoseobserved 2021HAL · Unilimdocument of 103 observations

3.33 %Of 3636 SickleScan® test results, 121 (3.33%) were phenotype misclassifications compared to high-performance liquid chromatography (HPLC).

Malidrépanocytoseobserved 2021HAL · Unilimdocument of 103 observations

11 %11% of the homozygous Sickle Cell Disease patients experience stroke by age of 20 years.

Malidrépanocytosepublished 2013BloodOpenAlexdocument of 10 observations

2,409 patientsAmong 2409 sickle cell disease patients in the CADRE cohort from Ivory Coast, Cameroon, and Mali, 1751 had the SS-Sβ0 phenotype and 658 had the SC-Sβ+ phenotype.

Cameroun · Côte d'Ivoire · Malidrépanocytosepublished 2015BloodOpenAlexdocument of 16 observations

81.67 %SickleScan® had a sensitivity of 81.67% to detect sickle cell disease compared to high-performance liquid chromatography.

MalidrépanocytoseHAL · Unilimdocument of 103 observations