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85 %Uncorrected adequate clinical and parasitological response (ACPR) in the intention-to-treat set was 85% for artesunate-pyronaridine (AP) at day 28.

Gabonpaludismepublished 2026The Lancet. Microbeeurope_pmcdocument of 21 observations

38 hoursFever was cleared within a median period of 38 hours in pediatric outpatients aged 1 to 14 years treated with fosmidomycin plus clindamycin for uncomplicated Plasmodium falciparum malaria.

Gabonpaludismepublished 2006Antimicrobial agents and chemotherapyeurope_pmcdocument of 8 observations

94 %In part A, the PCR-corrected adequate clinical and parasitological response at day 29 was 94% (95% CI 83–99) for the single-dose regimen of ganaplacide 800 mg plus lumefantrine-SDF 960 mg.

Gabonpaludismepublished 2023The Lancet. Infectious diseasesPubMeddocument of 10 observations

2.1 hazard_ratioOffspring of mothers with placental Plasmodium falciparum infection had a significantly higher risk of clinical malaria during the first 30 months of life, with an adjusted hazard ratio of 2.1.

Gabonpaludismepublished 2008Clinical infectious diseases : an official publication of the Infectious Diseases Society europe_pmcdocument of 4 observationsDOI 10.1086/591968

0.12 relative_riskThe relative risk of clinical malaria during pregnancy in the intervention group compared to the control group was 0.12.

Gabonpaludismepublished 2024The Lancet. Infectious diseasesPubMeddocument of 6 observations

759 parasites/μLLes densités parasitaires médianes étaient plus élevées chez les enfants porteurs de l’allèle APOE Ɛ4 comparés aux non-porteurs pour Plasmodium malariae (759 vs. 180 parasites/μL).

GabonpaludismeHAL · Unilimdocument of 81 observations

72 %The proportion of P. falciparum positive rapid diagnostic tests was 72% among school children in Lambaréné and surrounding villages in Gabon.

Gabonpaludismeobserved 2018published 2019Malaria journaleurope_pmcdocument of 8 observationsDOI 10.1186/s12936-019-3002-9

1,280 parasites/μLLes densités parasitaires médianes étaient significativement plus élevées chez les enfants porteurs de l’allèle APOE Ɛ4 comparés aux non-porteurs pour Plasmodium spp. (1280 vs. 640 parasites/μL).

GabonpaludismeHAL · Unilimdocument of 81 observations

96.84 %96.84% of Plasmodium sp. infections in urban areas were asymptomatic in south-east Gabon between April and July 2022.

Gabonpaludismeobserved April and July 2022published 2024Journal of parasitology researcheurope_pmcdocument of 5 observations

1,373 parasites/μLLa densité médiane du parasite du paludisme à forme asexuée chez les enfants uniquement positifs pour P. falciparum était de 1373 parasites/μL dans le groupe APOE Ɛ4, avec un intervalle interquartile de [362–4328].

GabonpaludismeHAL · Unilimdocument of 81 observations

0.04 ib/p/nThe nightly entomological inoculation rate (EIR) of Anopheles gambiae sensu stricto was 0.04 infectious bites per person per night in Ntoula.

Gabonpaludismeobserved June to September 2022published 2024Parasites & vectorseurope_pmcdocument of 12 observations

72.57 pg/mlIL-22 levels were 72.57 ± 7.5 pg/ml in infected children.

Gabonpaludismepublished 2017American journal of clinical and experimental immunologyeurope_pmcdocument of 9 observations

100 %The 3-day regimen achieved a 100% cure rate on day 28 (10/10).

Gabonpaludismeobserved day 28published 2005Antimicrobial agents and chemotherapyeurope_pmcdocument of 6 observations

7.4 nMThe mean concentration required to inhibit 50% of growth (IC50) of Plasmodium malariae with lumefantrine was 7.4 nM.

Gabonpaludismepublished 2025Pathogens (Basel, Switzerland)europe_pmcdocument of 4 observations

3 trialsIn 3 of the 7 trials with sufficient data, protected females had higher levels of antibodies to PfCSP than unprotected females.

Gabonpaludismepublished 2022Frontiers in immunologyPubMeddocument of 5 observations

13 %The prevalence of Plasmodium spp. infection was 13% in the Moyen-Ogooué province of Gabon.

Gabonpaludismepublished 2025PLoS neglected tropical diseaseseurope_pmcdocument of 11 observations

A recent epidemiological study in Gabon demonstrated a positive correlation between the prevalence of Plasmodium falciparum and the prevalence of individuals with sickle cell trait.

Gabonpaludisme · trait drépanocytaireobserved 2023HAL · Unilimdocument of 71 observations

3.3 %Plasmodium ovale was detected in 3.3% of febrile children in Makokou, Gabon.

Gabonpaludismepublished 2020The American journal of tropical medicine and hygieneeurope_pmcdocument of 16 observations

39.7 %La prévalence de Plasmodium spp. était de 39,7 % chez les enfants âgés de 1 à 4 ans, contre 53,4 % chez ceux âgés de 5 à 9 ans et 61,0 % chez ceux âgés de 10 à 12 ans.

GabonpaludismeHAL · Unilimdocument of 81 observations

69.6 %The prevalence of malaria infection was 69.6% among school-aged children in Gabon.

Gabonpaludismeobserved 2021published 2024Asymptomatic Malaria and Hidden Parasitic Burden in Gabonese Schoolchildren: Unveiling Sileurope_pmcdocument of 9 observations

21.9 %Parmi les 2 061 échantillons positifs pour le cytochrome b du Plasmodium, 326 (21,9 %) présentaient une infection à Plasmodium malariae.

GabonpaludismeHAL · Unilimdocument of 36 observations

14 %The GMZ2/alum candidate malaria vaccine had an efficacy of 14% against clinical malaria over 6 months of follow-up in a phase 2b multicentre trial in children 1–5 years of age.

Gabonpaludismepublished 2021VaccinePubMeddocument of 3 observations

16.9 daysThe time to parasitemia by thick blood smear was longer in lifelong malaria-exposed Gabonese adults with normal hemoglobin (geometric mean 16.9 days) than in nonimmune European controls (12.6 days).

Gabonpaludismepublished 2018The American journal of tropical medicine and hygieneeurope_pmcdocument of 12 observations

0 %Blood feeding rate with treated nets alone ranged from 0% to 16.93%.

Gabonpaludismepublished 2025Parasites & vectorseurope_pmcdocument of 4 observations

87.5 %PCR-corrected adequate clinical and parasitological response (ACPR) in the per-protocol set was 87.5% for artesunate-pyronaridine (AP) at day 42.

Gabonpaludismepublished 2026The Lancet. Microbeeurope_pmcdocument of 21 observations